Asset profile

Foralumab

Monoclonal antibody

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

Also in development:Secondary Progressive Multiple Sclerosis · Phase 2

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Competitive landscape

44 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 44 same-indication; 39 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Foralumab: this drugPhase 2Monoclonal antibodyCD3
Aldesleukin (Proleukin)ApprovedRecombinant Cytokine (il-2)Interleukin-2 receptor (IL-2R)
AlemtuzumabApprovedMonoclonal antibodyCD52
BafiertamApprovedSmall moleculeNrf2 pathway (fumaric acid ester)
Cladribine (MAVENCLAD®)ApprovedSmall moleculeAdenosine deaminase-resistant purine analog, DNA synthesis machinery in lymphocytes
CopaxoneApprovedPeptideMyelin basic protein-mimetic immunomodulation
Dimethyl Fumarate (Tecfidera)ApprovedSmall moleculeNrf2 pathway (fumaric acid ester)
Diroximel Fumarate (Vumerity)ApprovedSmall moleculeNrf2 pathway (fumaric acid ester)
DRFApprovedSmall moleculeNrf2 pathway (fumaric acid ester)
Fampridine (Ampyra / Fampyra)ApprovedSmall moleculePotassium Channel Blocker, Voltage-gated potassium channel (Kv), Voltage-gated potassium channels (Kv1/Shaker/KCNA family)
Fingolimod (Gilenya)ApprovedSmall moleculeSphingosine 1-phosphate receptor (S1PR, specifically S1P1), S1P receptor, Sphingosine-1-phosphate receptors (S1P1, S1P3, S1P4, S1P5)
Interferon Beta-1a (Avonex)ApprovedBiologic (subtype unspecified)Type I Interferon receptor (IFNAR)
Interferon Beta-1bApprovedBiologic (subtype unspecified)Interferon beta receptor (type I IFN signaling), Type I interferon receptor
Interferon-Beta1ApprovedBiologic (subtype unspecified)Type I interferon receptor
MayzentApprovedSmall moleculeS1P receptor
Natalizumab (Tysabri)ApprovedMonoclonal antibodyα4 integrin

…and 29 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (2)
April 2027 (1)
Phase 2Multiple System AtrophyRecruiting
Est. primary completion 2027-04-01 · NCT06868628 · CT.gov ↗
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July 2027 (1)
Phase 2ALS (Amyotrophic Lateral Sclerosis), ALS - Amyotrophic Lateral Sclerosis, ALSNot yet recruiting
Est. primary completion 2027-07 · NCT07688239 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (7)
Phase 1/2 (1)
Phase 1 (3)