Asset profile

olamkicept

Protein / enzyme therapeutic

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Evidence outlook · lead readout

NCT03235752 · Active Ulcerative Colitis

The completed lead evidence is positive, with design limits that temper confidence; the rationale below says which.

NCT03235752: The study was randomized, quadruple-blind, and placebo-controlled, with 91 participants, and its primary endpoint was a clinical and endoscopic measure. Because the registry provides no results for the Week 12 primary endpoint, the treatment effect cannot be judged from this record.

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 59 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Olamkicept: this drugPhase 2Protein / enzyme therapeuticIL-6 trans
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Aacf (Idacio)Approved—TNF-alpha
Adalimumab-Aaty (Yuflyma)Approved—TNF-alpha
Adalimumab-Adaz (Hyrimoz)Approved—TNF-alpha
Adalimumab-Adbm (Cyltezo)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Afzb (Abrilada)Approved—TNF-alpha
Adalimumab-Aqvh (Yusimry)Approved—TNF-alpha
Adalimumab-Atto (Amjevita)Approved—TNF-alpha
Adalimumab-Bwwd (Hadlima)Approved—TNF-alpha
Adalimumab-Fkjp (Hulio)Approved—TNF-alpha
Adalimumab-Ryvk (Simlandi)Approved—TNF-alpha
Balsalazide Disodium (Colazal)Approved—Aminosalicylate
Balsalazide Disodium (Giazo)Approved—Aminosalicylate
Budesonide (Uceris Rectal Foam)Approved—Glucocorticoid receptor
Budesonide MMX (Uceris)Approved—Glucocorticoid receptor

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (1)
Phase 1 (2)