Asset profile

Gotistobart

Monoclonal antibody

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Phase 3underway

Evidence outlook · registrational

Non-Small Cell Lung Cancer: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2027-08-31.

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Competitive landscape

63 competitors in this universe: 3 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 58 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Gotistobart: this drugPhase 3Monoclonal antibodyCTLA-4
TremelimumabApprovedMonoclonal antibodyCTLA-4
BotensilimabPhase 3Monoclonal antibodyCTLA-4
BA3071Phase 1/2Biologic (subtype unspecified)CTLA-4
Afatinib (Gilotrif)ApprovedSmall moleculeEGFR/HER1, HER2, HER4
Alectinib (Alecensa)ApprovedSmall moleculeALK
Alymsys (bevacizumab-Maly)ApprovedMonoclonal antibodyVEGF-A
AmivantamabApprovedMultispecific antibodyEGFR x c-MET
AtezolizumabApprovedMonoclonal antibodyPD-L1
BAT1706 (Avzivi)ApprovedMonoclonal antibodyVEGF-A
BAY2927088 (Hyrnuo)ApprovedSmall moleculeHER2 (ERBB2) exon 20 insertions and point mutations; also mutant-selective EGFR
BevacizumabApprovedMonoclonal antibodyVEGF-A, Vascular Endothelial Growth Factor Inhibitor
Bevacizumab-Awwb (MVASI)ApprovedMonoclonal antibodyVEGF-A
BinimetinibApprovedSmall moleculeMEK1/2
BrigatinibApprovedSmall moleculeALK
CapmatinibApprovedSmall moleculeMET

…and 48 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(5 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (2)
November 2026 (1)
Phase 1/2Metastatic Castration-resistant Prostate CancerActive not recruiting
Est. primary completion 2026-11-30 · NCT05682443 · CT.gov ↗
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December 2026 (1)
Phase 1/2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2026-12-31 · NCT04140526 · CT.gov ↗
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2027 (1)
August 2027 (1)
Phase 3Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-08-31 · NCT05671510 · CT.gov ↗
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2030 (1)
February 2030 (1)
Phase 1Non-Small Cell Lung CancerRecruiting
Est. primary completion 2030-02 · NCT05142189 · CT.gov ↗
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2036 (1)
July 2036 (1)
Phase 3Advanced Solid TumorEnrolling by invitation
Est. primary completion 2036-07-01 · NCT07659379 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (2)
Phase 2 (1)
Phase 1/2 (2)
Phase 1 (1)