Asset profile

Ceritinib

Small molecule

Preview Research free. Sign in to unlock 3 full asset or company pages every day, no card needed.Sign in to unlock this page
Approvedregulatory verdict

Evidence outlook

Approved: Non-Small Cell Lung Cancer

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Partial signal

How the evidence outlook works ↗

Competitive landscape

65 competitors in this universe: 5 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication.

Unlock with Research ↗
DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Ceritinib: this drugApprovedSmall moleculeALK
Alectinib (Alecensa)ApprovedSmall moleculeALK
BrigatinibApprovedSmall moleculeALK
EnsartinibApprovedSmall moleculeALK
Neladalkib NVL-655Phase 3Small moleculeALK
AQUA07Phase 1Small moleculeALK
Afatinib (Gilotrif)ApprovedSmall moleculeEGFR/HER1, HER2, HER4
Alymsys (bevacizumab-Maly)ApprovedMonoclonal antibodyVEGF-A
AmivantamabApprovedMultispecific antibodyEGFR x c-MET
AtezolizumabApprovedMonoclonal antibodyPD-L1
BAT1706 (Avzivi)ApprovedMonoclonal antibodyVEGF-A
BAY2927088 (Hyrnuo)ApprovedSmall moleculeHER2 (ERBB2) exon 20 insertions and point mutations; also mutant-selective EGFR
BevacizumabApprovedMonoclonal antibodyVEGF-A, Vascular Endothelial Growth Factor Inhibitor
Bevacizumab-Awwb (MVASI)ApprovedMonoclonal antibodyVEGF-A
BinimetinibApprovedSmall moleculeMEK1/2
CapmatinibApprovedSmall moleculeMET

…and 50 more. Research shows the complete landscape.

Research

Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(5 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 1ALK Positive, Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, ROS1 Gene Rearrangement …Active not recruiting
Est. primary completion 2026-12-31 · NCT02321501 · CT.gov ↗
What to watch
Unlock with Research ↗
2027 (2)
April 2027 (1)
Phase 1Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-04-09 · NCT02393625 · CT.gov ↗
What to watch
Unlock with Research ↗
June 2027 (1)
Phase 4ALK Positive MalignanciesActive not recruiting
Est. primary completion 2027-06-09 · NCT02584933 · CT.gov ↗
What to watch
Unlock with Research ↗
2028 (1)
February 2028 (1)
Phase 2Pancreatic Ductal Carcinoma, Advanced Cancer, Epithelial TumorRecruiting
Est. primary completion 2028-02-17 · NCT06813079 · CT.gov ↗
What to watch
Unlock with Research ↗
2030 (1)
September 2030 (1)
Phase 2NeuroblastomaRecruiting
Est. primary completion 2030-09 · NCT02559778 · CT.gov ↗
What to watch
Unlock with Research ↗

See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (3)
Phase 2 (18)
Phase 1/2 (2)
Phase 1 (16)
Phase 4 (1)
Appears in other studies (1)