Asset profile

Telisotuzumab Vedotin

Antibody–drug conjugate

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Approvedregulatory verdict

Evidence outlook

Approved: Non-Small Cell Lung Cancer

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

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Competitive landscape

73 competitors in this universe: 13 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Telisotuzumab Vedotin: this drugApprovedAntibody–drug conjugateMET
CapmatinibApprovedSmall moleculeMET
Tepotinib (Tepmetko)ApprovedSmall moleculeMET
ASKC202Phase 3Small moleculeMET
GlumetinibPhase 3Small moleculeMET
Savolitinib (Orpathys)Phase 3Small moleculeMET
Telisotuzumab AdizutecanPhase 3Antibody–drug conjugateMET
VebreltinibPhase 3Small moleculeMET
ABBV-400Phase 2Antibody–drug conjugateMET
RC108Phase 2Antibody–drug conjugateMET
CKD-703Phase 1/2Antibody–drug conjugateMET
REGN5093Phase 1/2Monoclonal antibodyMET
VERT-002Phase 1/2Monoclonal antibodyMET
DO-2Phase 1Small moleculeMET
Afatinib (Gilotrif)ApprovedSmall moleculeEGFR/HER1, HER2, HER4
Alectinib (Alecensa)ApprovedSmall moleculeALK

…and 58 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(3 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
February 2027 (1)
Phase 2Lung Non-Small Cell CarcinomaRecruiting
Est. primary completion 2027-02-01 · NCT07323641 · CT.gov ↗
What to watch
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2028 (2)
February 2028 (1)
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2028-02 · NCT06568939 · CT.gov ↗
What to watch
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December 2028 (1)
Phase 3Non-Small Cell Lung CancerRecruiting
Est. primary completion 2028-12 · NCT04928846 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (2)
Phase 2 (5)
Phase 1 (2)