Asset profile
Cemiplimab
Monoclonal antibody
Approvedregulatory verdict
Evidence outlook
Approved: Non-Small Cell Lung Cancer
Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.
track record: Partial signal
How the evidence outlook works ↗
Featured trials
The studies most instrumental to this drug's clinical progression, individually graded on design and result. Pick an indication; Research unlocks the trials, endpoints, key results and grades.
Competitive landscape
83 competitors in this universe: 22 direct rivals (same mechanism and indication), 1 same-class, 60 same-indication.
Unlock with Research ↗
| Drug | Stage | Modality | Mechanism | Evidence signal | Reported efficacygraded featured trials |
|---|---|---|---|---|---|
| Cemiplimab: this drug | Approved | Monoclonal antibody | PD-1 | ||
| Nivolumab | Approved | Monoclonal antibody | PD-1 | ||
| Opdivo Qvantig | Approved | Monoclonal antibody | PD-1 | ||
| Pembrolizumab | Approved | Monoclonal antibody | PD-1 | ||
| Pembrolizumab Berahyaluronidase Alfa | Approved | Monoclonal antibody | PD-1 | ||
| Retifanlimab | Approved | Monoclonal antibody | PD-1 | ||
| Toripalimab | Approved | Monoclonal antibody | PD-1 | ||
| Abp 234 | Phase 3 | Monoclonal antibody | PD-1 | ||
| Balstilimab | Phase 3 | Monoclonal antibody | PD-1 | ||
| Camrelizumab | Phase 3 | Monoclonal antibody | PD-1 | ||
| Cetrelimab | Phase 3 | Monoclonal antibody | PD-1 | ||
| CT-P51 | Phase 3 | Small molecule | PD-1 | ||
| Dostarlimab | Phase 3 | Monoclonal antibody | PD-1 | ||
| Enlonstobart | Phase 3 | Monoclonal antibody | PD-1 | ||
| MB12 | Phase 3 | Monoclonal antibody | PD-1 | ||
| Penpulimab | Phase 3 | Monoclonal antibody | PD-1 |
…and 68 more. Research shows the complete landscape.
Research
Unlock with Research ↗Unlock the full comparison
Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.
Compare head-to-head
vs Nivolumab · Non-Small Cell Lung Cancervs Pembrolizumab · Non-Small Cell Lung Cancervs Retifanlimab · Non-Small Cell Lung Cancervs Toripalimab · Non-Small Cell Lung Cancervs Camrelizumab · Non-Small Cell Lung Cancervs Dostarlimab · Non-Small Cell Lung Cancer
16 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.
Upcoming events
(122 total)
Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.
2026 (10)
October 2026 (2)
Phase 2Cutaneous Squamous Cell Carcinoma, Skin Cancer, Squamous Cell Carcinoma, Locally Advanced Squamous Cell Carcinoma …Active not recruiting
Est. primary completion 2026-10-06 · NCT05574101 · CT.gov ↗
What to watch
Phase 1Advanced Solid TumorRecruiting
Est. primary completion 2026-10-30 · NCT06302426 · CT.gov ↗
What to watch
November 2026 (3)
Phase 2Prostate Cancer MetastaticActive not recruiting
Est. primary completion 2026-11 · NCT03951831 · CT.gov ↗
What to watch
Phase 2MelanomaActive not recruiting
Est. primary completion 2026-11-02 · NCT06190951 · CT.gov ↗
What to watch
Phase 1/2Advanced Solid TumorsActive not recruiting
Est. primary completion 2026-11-13 · NCT04626635 · CT.gov ↗
What to watch
December 2026 (5)
Phase 1/2Prostate CancerActive not recruiting
Est. primary completion 2026-12 · NCT04989946 · CT.gov ↗
What to watch
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2026-12 · NCT06623656 · CT.gov ↗
What to watch
Phase 1/2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2026-12-01 · NCT06088771 · CT.gov ↗
What to watch
Phase 1/2GlioblastomaActive not recruiting
Est. primary completion 2026-12-31 · NCT03491683 · CT.gov ↗
What to watch
Phase 2Recurrent Skin Squamous Cell Carcinoma, Resectable Skin Squamous Cell Carcinoma, Stage I Skin Cancer, Stage II Skin Cancer …Active not recruiting
Est. primary completion 2026-12-31 · NCT04315701 · CT.gov ↗
What to watch
2027 (37)
January 2027 (2)
Phase 2Advanced Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8 …Recruiting
Est. primary completion 2027-01-01 · NCT06731270 · CT.gov ↗
What to watch
Phase 2Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Metastatic Carcinoma in the LiverRecruiting
Est. primary completion 2027-01-30 · NCT06860815 · CT.gov ↗
What to watch
February 2027 (2)
March 2027 (2)
April 2027 (4)
Phase 1Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-04 · NCT06171750 · CT.gov ↗
What to watch
Phase 1/2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-04 · NCT06162572 · CT.gov ↗
What to watch
Phase 1/2Advanced Solid MalignancyRecruiting
Est. primary completion 2027-04-30 · NCT06923761 · CT.gov ↗
What to watch
Phase 2Colon CancerActive not recruiting
Est. primary completion 2027-04-30 · NCT05961709 · CT.gov ↗
What to watch
May 2027 (6)
Phase 1Prostate CancerRecruiting
Est. primary completion 2027-05-01 · NCT06826768 · CT.gov ↗
What to watch
Phase 1Advanced Solid Tumor, Metastatic Solid TumorRecruiting
Est. primary completion 2027-05-05 · NCT05259709 · CT.gov ↗
What to watch
Phase 1/2Recurrent Ovarian Cancer, Recurrent Fallopian Tube Cancer, Recurrent Primary Peritoneal Cancer, Recurrent Endometrial Cancer …Recruiting
Est. primary completion 2027-05-10 · NCT03564340 · CT.gov ↗
What to watch
Phase 2Locally Recurrent Oral Cavity Squamous Cell CarcinomaRecruiting
Est. primary completion 2027-05-15 · NCT06448026 · CT.gov ↗
What to watch
Phase 2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-05-20 · NCT06465329 · CT.gov ↗
What to watch
Phase 2Advanced Dedifferentiated Liposarcoma, Locally Advanced Dedifferentiated Liposarcoma, Metastatic Dedifferentiated Liposarcoma …Active not recruiting
Est. primary completion 2027-05-31 · NCT05694871 · CT.gov ↗
What to watch
June 2027 (3)
Phase 3Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-06-01 · NCT05317858 · CT.gov ↗
What to watch
Phase 1Head and Neck Cancer, Head Cancer, Head Cancer Neck, Neck Cancer, Head and Neck Squamous Cell Carcinoma, HNSCCRecruiting
Est. primary completion 2027-06-20 · NCT04722523 · CT.gov ↗
What to watch
Phase 2HPV-Related Squamous Cell CarcinomaRecruiting
Est. primary completion 2027-06-30 · NCT04988074 · CT.gov ↗
What to watch
July 2027 (2)
August 2027 (1)
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-08 · NCT06865339 · CT.gov ↗
What to watch
September 2027 (6)
Phase 2Advanced MelanomaRecruiting
Est. primary completion 2027-09 · NCT06594991 · CT.gov ↗
What to watch
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-09-01 · NCT04253964 · CT.gov ↗
What to watch
Phase 2/3Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-09-28 · NCT05785767 · CT.gov ↗
What to watch
Phase 1Advanced MalignanciesActive not recruiting
Est. primary completion 2027-09-30 · NCT03233139 · CT.gov ↗
What to watch
Phase 1/2Metastatic Colorectal Adenocarcinoma, Refractory Colorectal Adenocarcinoma, Stage III Colorectal Cancer AJCC v8 …Recruiting
Est. primary completion 2027-09-30 · NCT07147231 · CT.gov ↗
What to watch
Phase 2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-09-30 · NCT05208944 · CT.gov ↗
What to watch
October 2027 (1)
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-10 · NCT07264673 · CT.gov ↗
What to watch
November 2027 (2)
Phase 1/2Metastatic Castration-Resistant Prostate Cancer (mCRPC), Clear Cell Renal Cell Carcinoma (ccRCC)Recruiting
Est. primary completion 2027-11-15 · NCT03972657 · CT.gov ↗
What to watch
Phase 2Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma, Laryngeal Squamous Cell Carcinoma …Recruiting
Est. primary completion 2027-11-24 · NCT06980038 · CT.gov ↗
What to watch
December 2027 (6)
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-12 · NCT06449313 · CT.gov ↗
What to watch
Early phase / not applicableNon-Small Cell Lung CancerRecruiting
Est. primary completion 2027-12 · NCT06743581 · CT.gov ↗
What to watch
Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2027-12-01 · NCT07450183 · CT.gov ↗
What to watch
Phase 2Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck …Active not recruiting
Est. primary completion 2027-12-31 · NCT03565783 · CT.gov ↗
What to watch
Phase 2Leiomyosarcoma, SarcomaRecruiting
Est. primary completion 2027-12-31 · NCT06528769 · CT.gov ↗
What to watch
Phase 2/3Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8Recruiting
Est. primary completion 2027-12-31 · NCT06616584 · CT.gov ↗
What to watch
2028 (34)
January 2028 (5)
Phase 2Melanoma BRAF V600E/K Mutated, Melanoma and Brain MetastasesRecruiting
Est. primary completion 2028-01 · NCT06887088 · CT.gov ↗
What to watch
Phase 2Colon and Rectal CancerRecruiting
Est. primary completion 2028-01 · NCT07433673 · CT.gov ↗
What to watch
Phase 1Lung CancerActive not recruiting
Est. primary completion 2028-01-01 · NCT05704634 · CT.gov ↗
What to watch
Phase 3Cutaneous Squamous Cell CarcinomaActive not recruiting
Est. primary completion 2028-01-07 · NCT03969004 · CT.gov ↗
What to watch
Phase 2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2028-01-26 · NCT05557591 · CT.gov ↗
What to watch
February 2028 (3)
Phase 2Renal Cell CarcinomaRecruiting
Est. primary completion 2028-02 · NCT06699602 · CT.gov ↗
What to watch
Phase 1Solid Tumor, Locally Advanced Solid Tumor, Metastatic TumorRecruiting
Est. primary completion 2028-02-28 · NCT07404332 · CT.gov ↗
What to watch
March 2028 (4)
Phase 1Merkel Cell Carcinoma, Cutaneous Squamous Cell CarcinomaRecruiting
Est. primary completion 2028-03 · NCT04975152 · CT.gov ↗
What to watch
Phase 2Head and Neck Squamous Cell CarcinomaActive not recruiting
Est. primary completion 2028-03 · NCT06855212 · CT.gov ↗
What to watch
Phase 1Multiple MyelomaRecruiting
Est. primary completion 2028-03-25 · NCT05137054 · CT.gov ↗
What to watch
Phase 1Anaplastic Thyroid Cancer, Thyroid Cancer, BRAF Mutation-Related TumorsRecruiting
Est. primary completion 2028-03-31 · NCT06902376 · CT.gov ↗
What to watch
May 2028 (3)
Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2028-05 · NCT07418931 · CT.gov ↗
What to watch
Phase 2Pleural MesotheliomasRecruiting
Est. primary completion 2028-05 · NCT07234058 · CT.gov ↗
What to watch
Phase 2MelanomaNot yet recruiting
Est. primary completion 2028-05-24 · NCT07511036 · CT.gov ↗
What to watch
June 2028 (3)
Phase 2Pancreatic Cancer, Adenocarcinoma of the Pancreas, AdenocarcinomaActive not recruiting
Est. primary completion 2028-06 · NCT04543071 · CT.gov ↗
What to watch
Phase 2Head and Neck Squamous Cell Carcinoma (HNSCC)Recruiting
Est. primary completion 2028-06-04 · NCT06769698 · CT.gov ↗
What to watch
Phase 2Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal CancerRecruiting
Est. primary completion 2028-06-30 · NCT06787612 · CT.gov ↗
What to watch
July 2028 (2)
September 2028 (3)
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2028-09 · NCT07020065 · CT.gov ↗
What to watch
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2028-09 · NCT06656598 · CT.gov ↗
What to watch
Phase 2Solid TumorsRecruiting
Est. primary completion 2028-09-01 · NCT06651593 · CT.gov ↗
What to watch
October 2028 (1)
Phase 2Basal Cell Carcinoma (BCC), First Line TreatmentRecruiting
Est. primary completion 2028-10 · NCT06981325 · CT.gov ↗
What to watch
November 2028 (2)
December 2028 (8)
Phase 1/2Cutaneous Basal Cell CarcinomaRecruiting
Est. primary completion 2028-12 · NCT07251413 · CT.gov ↗
What to watch
Phase 2Vulvar CancersNot yet recruiting
Est. primary completion 2028-12 · NCT07101848 · CT.gov ↗
What to watch
Phase 2Bladder Cancer, Muscle-Invasive Bladder CarcinomaRecruiting
Est. primary completion 2028-12 · NCT06571708 · CT.gov ↗
What to watch
Phase 2Penile CancerNot yet recruiting
Est. primary completion 2028-12 · NCT07101822 · CT.gov ↗
What to watch
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2028-12 · NCT07360743 · CT.gov ↗
What to watch
Phase 1B-Cell Non-Hodgkin Lymphoma, Histiocytic and Dendritic Cell Neoplasm, Myelodysplastic Syndrome …Recruiting
Est. primary completion 2028-12-31 · NCT03017820 · CT.gov ↗
What to watch
Phase 1Peripheral T Cell Lymphoma, Relapsed Peripheral T-Cell Lymphoma, Peripheral T-Cell Lymphoma, Not Otherwise Specified …Recruiting
Est. primary completion 2028-12-31 · NCT06508463 · CT.gov ↗
What to watch
Phase 2Colon CancerNot yet recruiting
Est. primary completion 2028-12-31 · NCT07224022 · CT.gov ↗
What to watch
2029 (15)
February 2029 (1)
Phase 2Melanoma (Skin)Not yet recruiting
Est. primary completion 2029-02-01 · NCT07527325 · CT.gov ↗
What to watch
March 2029 (3)
Phase 3Non-Small Cell Lung CancerRecruiting
Est. primary completion 2029-03 · NCT06931717 · CT.gov ↗
What to watch
Phase 1/2Metastatic Colorectal Cancer, KRAS G12C MutationsRecruiting
Est. primary completion 2029-03-01 · NCT06412198 · CT.gov ↗
What to watch
April 2029 (1)
Phase 2Colo-rectal CancerRecruiting
Est. primary completion 2029-04-17 · NCT07058012 · CT.gov ↗
What to watch
May 2029 (1)
Phase 2Cutaneous Squamous Cell Carcinoma, Cutaneous Squamous Cell Carcinoma of the Head and Neck, Neoplasms, Non-melanoma Skin CancerActive not recruiting
Est. primary completion 2029-05 · NCT05878288 · CT.gov ↗
What to watch
June 2029 (1)
Phase 2Locally Advanced Adrenal Cortical Carcinoma, Metastatic Adrenal Cortical Carcinoma, Recurrent Adrenal Cortical Carcinoma …Recruiting
Est. primary completion 2029-06-02 · NCT06900595 · CT.gov ↗
What to watch
August 2029 (1)
Phase 2Clear Cell Renal Cell CarcinomaRecruiting
Est. primary completion 2029-08 · NCT07223541 · CT.gov ↗
What to watch
October 2029 (1)
Phase 2MelanomaEnrolling by invitation
Est. primary completion 2029-10-10 · NCT06848088 · CT.gov ↗
What to watch
November 2029 (3)
Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2029-11-01 · NCT07720167 · CT.gov ↗
What to watch
Phase 2Head and Neck CancerRecruiting
Est. primary completion 2029-11-30 · NCT07179315 · CT.gov ↗
What to watch
Phase 2Advanced Renal Cell Carcinoma (aRCC), Metastatic Renal Cell Carcinoma ( mRCC), Clear Cell Renal Cell Carcinoma (ccRCC)Recruiting
Est. primary completion 2029-11-30 · NCT07188896 · CT.gov ↗
What to watch
December 2029 (3)
Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2029-12-01 · NCT07808138 · CT.gov ↗
What to watch
Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2029-12-31 · NCT07274384 · CT.gov ↗
What to watch
Phase 2Merkel Cell Carcinoma, Stage I, Merkel Cell Carcinoma, Stage II, Neoadjuvant ImmunotherapyRecruiting
Est. primary completion 2029-12-31 · NCT07387198 · CT.gov ↗
What to watch
2030 (20)
January 2030 (2)
February 2030 (2)
May 2030 (3)
Phase 2Colorectal CancerRecruiting
Est. primary completion 2030-05 · NCT06205836 · CT.gov ↗
What to watch
Phase 3Cutaneous Squamous Cell Carcinoma (CSCC)Recruiting
Est. primary completion 2030-05-03 · NCT06585410 · CT.gov ↗
What to watch
Phase 1Epithelial Ovarian Cancer, Primary Peritoneal Carcinoma, Fallopian Tube CancerRecruiting
Est. primary completion 2030-05-27 · NCT06469281 · CT.gov ↗
What to watch
June 2030 (1)
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2030-06-25 · NCT07603856 · CT.gov ↗
What to watch
July 2030 (2)
September 2030 (3)
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2030-09 · NCT07001618 · CT.gov ↗
What to watch
Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2030-09-01 · NCT07746388 · CT.gov ↗
What to watch
Phase 2Anaplastic Thyroid CancerNot yet recruiting
Est. primary completion 2030-09-01 · NCT07470489 · CT.gov ↗
What to watch
October 2030 (3)
Phase 1Metastatic Skin Squamous Cell Carcinoma, Recurrent Skin Squamous Cell CarcinomaActive not recruiting
Est. primary completion 2030-10-01 · NCT04428671 · CT.gov ↗
What to watch
Phase 1/2Metastatic Castration-Resistant Prostate Cancer (mCRPC), Clear Cell Renal Cell Carcinoma (ccRCC)Recruiting
Est. primary completion 2030-10-27 · NCT07594106 · CT.gov ↗
What to watch
Phase 2Metastatic Uveal MelanomaRecruiting
Est. primary completion 2030-10-31 · NCT06121180 · CT.gov ↗
What to watch
November 2030 (1)
Phase 2Metastatic NUT Carcinoma, Unresectable NUT CarcinomaRecruiting
Est. primary completion 2030-11-20 · NCT07050186 · CT.gov ↗
What to watch
December 2030 (3)
Phase 2Breast Neoplasms, Breast Cancer, Breast Tumors, Angiosarcoma, TNBC - Triple-Negative Breast Cancer, HER2-positive Breast Cancer …Recruiting
Est. primary completion 2030-12 · NCT01042379 · CT.gov ↗
What to watch
Phase 2Lung Non-Small Cell Carcinoma, Stage IB Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8 …Recruiting
Est. primary completion 2030-12-02 · NCT06918132 · CT.gov ↗
What to watch
Phase 2Sinonasal Squamous Cell Carcinoma, Stage III Sinonasal Cancer AJCC v8, Stage IVA Sinonasal Cancer AJCC v8 …Recruiting
Est. primary completion 2030-12-16 · NCT07281417 · CT.gov ↗
What to watch
2031 (4)
February 2031 (1)
Phase 2Glioblastoma, Glioblastoma, IDH-wildtype, Glioblastoma IDH (Isocitrate Dehydrogenase) WildtypeNot yet recruiting
Est. primary completion 2031-02-28 · NCT07620548 · CT.gov ↗
What to watch
March 2031 (1)
Phase 2Kidney Transplant Recipient, Cutaneous Squamous Cell Carcinoma (CSCC), Advanced Cutaneous Squamous Cell Carcinoma, Kidney TransplantNot yet recruiting
Est. primary completion 2031-03-31 · NCT07715734 · CT.gov ↗
What to watch
August 2031 (1)
Phase 2Squamous Cell CarcinomaNot yet recruiting
Est. primary completion 2031-08-22 · NCT07346196 · CT.gov ↗
What to watch
December 2031 (1)
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2031-12-30 · NCT06917573 · CT.gov ↗
What to watch
2032 (1)
August 2032 (1)
Phase 1/2High-Grade Glioma (HGG), Posterior Fossa-A EpendymomaNot yet recruiting
Est. primary completion 2032-08-27 · NCT07567469 · CT.gov ↗
What to watch
2033 (1)
February 2033 (1)
Phase 2Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 …Recruiting
Est. primary completion 2033-02-01 · NCT07195734 · CT.gov ↗
What to watch
All registered studies
Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.