Asset profile

Ipilimumab

Monoclonal antibody

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Approvedregulatory verdict

Evidence outlook

Approved: Non-Small Cell Lung Cancer

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Partial signal

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Ipilimumab: this drugApprovedMonoclonal antibodyCTLA-4 antagonist
Afatinib (Gilotrif)ApprovedSmall moleculeEGFR/HER1, HER2, HER4
Alectinib (Alecensa)ApprovedSmall moleculeALK
Alymsys (bevacizumab-Maly)ApprovedMonoclonal antibodyVEGF-A
AmivantamabApprovedMultispecific antibodyEGFR x c-MET
AtezolizumabApprovedMonoclonal antibodyPD-L1
BAT1706 (Avzivi)ApprovedMonoclonal antibodyVEGF-A
BAY2927088 (Hyrnuo)ApprovedSmall moleculeHER2 (ERBB2) exon 20 insertions and point mutations; also mutant-selective EGFR
BevacizumabApprovedMonoclonal antibodyVEGF-A, Vascular Endothelial Growth Factor Inhibitor
Bevacizumab-Awwb (MVASI)ApprovedMonoclonal antibodyVEGF-A
BinimetinibApprovedSmall moleculeMEK1/2
BrigatinibApprovedSmall moleculeALK
CapmatinibApprovedSmall moleculeMET
CemiplimabApprovedMonoclonal antibodyPD-1
CeritinibApprovedSmall moleculeALK
CrizotinibApprovedSmall moleculeALK, ROS1, MET/HGFR, and RON

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(161 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (19)
October 2026 (1)
Phase 1Advanced Clear Cell Renal Cell Carcinoma, Advanced Renal Cell Carcinoma, Advanced Sarcomatoid Renal Cell Carcinoma …Recruiting
Est. primary completion 2026-10-19 · NCT06399419 · CT.gov ↗
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November 2026 (3)
Phase 2Melanoma, Brain MetastasesRecruiting
Est. primary completion 2026-11 · NCT06712927 · CT.gov ↗
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Phase 1/2Renal Cell CarcinomaActive not recruiting
Est. primary completion 2026-11-01 · NCT05501054 · CT.gov ↗
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Phase 1/2GlioblastomaActive not recruiting
Est. primary completion 2026-11-17 · NCT03233152 · CT.gov ↗
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December 2026 (15)
Phase 1Stage IV Small Cell Lung CancerActive not recruiting
Est. primary completion 2026-12 · NCT03223155 · CT.gov ↗
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Phase 1/2Uveal Melanoma, MetastaticActive not recruiting
Est. primary completion 2026-12 · NCT04283890 · CT.gov ↗
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Phase 2Pleural Biphasic Mesothelioma, Pleural Sarcomatoid MesotheliomaRecruiting
Est. primary completion 2026-12-15 · NCT05647265 · CT.gov ↗
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Phase 2Papillary Renal Cell Carcinoma, Unclassified Renal Cell Carcinoma, Translocation Renal Cell Carcinoma, Chromophobe Renal Cell Carcinoma …Active not recruiting
Est. primary completion 2026-12-20 · NCT04413123 · CT.gov ↗
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Phase 1Glioblastoma, GBM, Glioblastoma Multiforme, Grade IV AstrocytomaActive not recruiting
Est. primary completion 2026-12-30 · NCT04606316 · CT.gov ↗
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Phase 2Genitourinary Cancer, Adrenocortical Carcinoma, Non-urothelial Bladder, Non-urothelial Upper Tract, Penile Cancer …Active not recruiting
Est. primary completion 2026-12-30 · NCT03333616 · CT.gov ↗
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Phase 2Clinical Stage 0 Gastric Cancer AJCC v8, Clinical Stage 0 Gastroesophageal Junction Adenocarcinoma AJCC v8 …Active not recruiting
Est. primary completion 2026-12-30 · NCT03776487 · CT.gov ↗
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Phase 1Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8 …Recruiting
Est. primary completion 2026-12-31 · NCT06324240 · CT.gov ↗
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Phase 1Clear Cell Renal Cell Carcinoma, Metastatic Kidney Carcinoma, Stage IV Renal Cell Cancer AJCC v7Active not recruiting
Est. primary completion 2026-12-31 · NCT02210117 · CT.gov ↗
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Phase 1Aggressive Variant Prostate Carcinoma, Castration-Resistant Prostate Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma …Active not recruiting
Est. primary completion 2026-12-31 · NCT04388852 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2026-12-31 · NCT05597800 · CT.gov ↗
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Phase 2Lymphoma, Non-Hodgkin, Multiple Myeloma, Advanced Solid TumorsRecruiting
Est. primary completion 2026-12-31 · NCT03297606 · CT.gov ↗
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Phase 2Advanced Acral Melanoma, Advanced Cutaneous Melanoma, Advanced Mucosal Melanoma, Clinical Stage IV Cutaneous Melanoma AJCC v8 …Recruiting
Est. primary completion 2026-12-31 · NCT07155317 · CT.gov ↗
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Phase 2Uterine Cervical NeoplasmsRecruiting
Est. primary completion 2026-12-31 · NCT05492123 · CT.gov ↗
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Phase 2Astrocytoma, IDH-Mutant, Grade 4, Diffuse Glioma, Glioblastoma, IDH-Wildtype, Secondary GlioblastomaActive not recruiting
Est. primary completion 2026-12-31 · NCT04145115 · CT.gov ↗
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2027 (71)
January 2027 (10)
Phase 2Microsatellite Stable Colorectal Cancer, Pancreatic Cancer, MSI High Colorectal CancerActive not recruiting
Est. primary completion 2027-01 · NCT03104439 · CT.gov ↗
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Phase 2Bladder CancerActive not recruiting
Est. primary completion 2027-01 · NCT03520491 · CT.gov ↗
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Phase 1Glioblastoma, Gliosarcoma, Adult, Glioblastoma - CategoryRecruiting
Est. primary completion 2027-01-01 · NCT07134842 · CT.gov ↗
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Phase 1/2Solid TumorRecruiting
Est. primary completion 2027-01-19 · NCT05584670 · CT.gov ↗
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Phase 2ICB-refractory MelanomaActive not recruiting
Est. primary completion 2027-01-23 · NCT06250335 · CT.gov ↗
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Phase 1Pancreatic Adenocarcinoma, Stage II Pancreatic Cancer AJCC v8, Stage III Pancreatic Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8Active not recruiting
Est. primary completion 2027-01-31 · NCT03816358 · CT.gov ↗
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Phase 1Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-01-31 · NCT05176483 · CT.gov ↗
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Phase 1/2Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8 …Recruiting
Est. primary completion 2027-01-31 · NCT05896839 · CT.gov ↗
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Phase 2Malignant Melanoma, Melanoma (Skin), Melanoma Stage III, Melanoma Stage IVActive not recruiting
Est. primary completion 2027-01-31 · NCT04079166 · CT.gov ↗
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Phase 2Advanced Melanoma, Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8 …Active not recruiting
Est. primary completion 2027-01-31 · NCT04462406 · CT.gov ↗
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February 2027 (5)
Phase 1/2Atypical Teratoid Rhabdoid Tumor, INI1 (SMARCB1)-Deficient Primary CNS Malignant Tumors, SMARCA4-deficient Primary CNS Malignant Tumors …Active not recruiting
Est. primary completion 2027-02-01 · NCT05407441 · CT.gov ↗
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Phase 2Metastatic Soft-tissue SarcomaActive not recruiting
Est. primary completion 2027-02-01 · NCT04551430 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-02-05 · NCT06946797 · CT.gov ↗
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Phase 1/2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-02-28 · NCT06047379 · CT.gov ↗
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Phase 2Bladder Adenocarcinoma, Bladder Clear Cell Adenocarcinoma, Bladder Mixed Adenocarcinoma, Bladder Neuroendocrine Carcinoma …Recruiting
Est. primary completion 2027-02-28 · NCT03866382 · CT.gov ↗
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March 2027 (8)
Phase 2Hepatocellular Carcinoma (HCC)Recruiting
Est. primary completion 2027-03 · NCT07422753 · CT.gov ↗
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Phase 2/3Colorectal NeoplasmsActive not recruiting
Est. primary completion 2027-03 · NCT05141721 · CT.gov ↗
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Phase 1Locally Advanced or Metastatic MelanomaRecruiting
Est. primary completion 2027-03-04 · NCT05498792 · CT.gov ↗
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Phase 2Melanoma, Melanoma Stage IIIActive not recruiting
Est. primary completion 2027-03-11 · NCT05289193 · CT.gov ↗
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Phase 3Renal Cell CarcinomaActive not recruiting
Est. primary completion 2027-03-11 · NCT03873402 · CT.gov ↗
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Phase 1/2Grade 2 Meningioma, Grade 3 Meningioma, Recurrent MeningiomaActive not recruiting
Est. primary completion 2027-03-19 · NCT03604978 · CT.gov ↗
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Phase 3Lung Adenocarcinoma, Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8Active not recruiting
Est. primary completion 2027-03-31 · NCT03391869 · CT.gov ↗
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Early phase / not applicableMetastatic Melanoma, Skin CancerRecruiting
Est. primary completion 2027-03-31 · NCT07422779 · CT.gov ↗
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April 2027 (10)
Phase 2Colorectal Cancer Metastatic, MSI-H Colorectal CancerActive not recruiting
Est. primary completion 2027-04 · NCT04730544 · CT.gov ↗
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Phase 2HCC - Hepatocellular Carcinoma, Conversion TherapyRecruiting
Est. primary completion 2027-04 · NCT07560488 · CT.gov ↗
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Phase 2Metastatic MelanomaActive not recruiting
Est. primary completion 2027-04 · NCT03122522 · CT.gov ↗
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Phase 1Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-04-01 · NCT05254184 · CT.gov ↗
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Phase 2Esophageal Squamous Cell Carcinoma (ESCC)Recruiting
Est. primary completion 2027-04-01 · NCT07751055 · CT.gov ↗
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Phase 2Nasopharyngeal CarcinomaActive not recruiting
Est. primary completion 2027-04-05 · NCT03097939 · CT.gov ↗
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Phase 1Squamous Cell Carcinoma of the Head and NeckActive not recruiting
Est. primary completion 2027-04-09 · NCT03690986 · CT.gov ↗
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Phase 1/2Solid Tumor, Metastases to Soft TissueActive not recruiting
Est. primary completion 2027-04-23 · NCT03707808 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-04-27 · NCT06364917 · CT.gov ↗
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Phase 2Bone Sarcoma, Dedifferentiated Chondrosarcoma, Giant Cell Tumor of Bone, Malignancy in Giant Cell Tumor of Bone, Malignant Solid Neoplasm …Active not recruiting
Est. primary completion 2027-04-30 · NCT03449108 · CT.gov ↗
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May 2027 (3)
Phase 2Mucosal MelanomaRecruiting
Est. primary completion 2027-05 · NCT05384496 · CT.gov ↗
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Phase 1Metastatic Colorectal Cancer (CRC), Locally Advanced Colorectal Cancer, Metastatic Pancreatic Cancer, Locally Advanced Pancreatic CancerNot yet recruiting
Est. primary completion 2027-05-01 · NCT07587827 · CT.gov ↗
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Phase 1Clear Cell Renal Cell Carcinoma, Sarcomatoid Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8Active not recruiting
Est. primary completion 2027-05-25 · NCT06049576 · CT.gov ↗
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June 2027 (6)
Phase 2Breast CancerActive not recruiting
Est. primary completion 2027-06 · NCT03546686 · CT.gov ↗
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Phase 2MesotheliomaActive not recruiting
Est. primary completion 2027-06 · NCT03918252 · CT.gov ↗
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Phase 1Colorectal Cancer, Pancreatic CancerActive not recruiting
Est. primary completion 2027-06-01 · NCT04117087 · CT.gov ↗
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Phase 1/2Recurrent Classic Hodgkin Lymphoma, Refractory Classic Hodgkin LymphomaActive not recruiting
Est. primary completion 2027-06-30 · NCT01896999 · CT.gov ↗
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Phase 2Acral Lentiginous Melanoma, Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Cutaneous Melanoma …Recruiting
Est. primary completion 2027-06-30 · NCT04511013 · CT.gov ↗
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Phase 2Locally Advanced Rectal Adenocarcinoma, Stage II Rectal Cancer AJCC v8, Stage III Rectal Cancer AJCC v8Active not recruiting
Est. primary completion 2027-06-30 · NCT04751370 · CT.gov ↗
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July 2027 (2)
Phase 2Cancer of RectumRecruiting
Est. primary completion 2027-07 · NCT05732389 · CT.gov ↗
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Phase 2Basal Cell CarcinomaRecruiting
Est. primary completion 2027-07 · NCT03521830 · CT.gov ↗
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August 2027 (4)
Phase 1Melanoma (Skin)Active not recruiting
Est. primary completion 2027-08 · NCT06377111 · CT.gov ↗
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Phase 2MelanomaRecruiting
Est. primary completion 2027-08 · NCT06365619 · CT.gov ↗
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Phase 1Lymphoma, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm, Unresectable Malignant Solid NeoplasmActive not recruiting
Est. primary completion 2027-08-01 · NCT03502733 · CT.gov ↗
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Phase 1Hepatocellular Carcinoma (HCC)Recruiting
Est. primary completion 2027-08-01 · NCT07075120 · CT.gov ↗
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September 2027 (5)
Phase 2Cancer, Tumors, Neoplasm, NeoplasiaRecruiting
Est. primary completion 2027-09 · NCT02925234 · CT.gov ↗
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Phase 2Advanced MelanomaRecruiting
Est. primary completion 2027-09 · NCT06594991 · CT.gov ↗
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Phase 1Clinical Stage I Cutaneous Melanoma AJCC v8, Clinical Stage IA Cutaneous Melanoma AJCC v8, Clinical Stage IB Cutaneous Melanoma AJCC v8 …Recruiting
Est. primary completion 2027-09-30 · NCT04697576 · CT.gov ↗
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Phase 1Advanced MalignanciesActive not recruiting
Est. primary completion 2027-09-30 · NCT03233139 · CT.gov ↗
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Phase 2Leukemia, Myelodysplastic Syndrome, Recurrent Myelodysplastic SyndromeActive not recruiting
Est. primary completion 2027-09-30 · NCT02530463 · CT.gov ↗
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October 2027 (5)
Phase 2Metastatic Cancer, Melanoma Cancer, Lung Cancer, Bladder Cancer, Renal Cancer, Head/Neck CancersActive not recruiting
Est. primary completion 2027-10 · NCT03693014 · CT.gov ↗
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Phase 2Advanced Clear Cell Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8 …Recruiting
Est. primary completion 2027-10-01 · NCT05361720 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-10-15 · NCT05012254 · CT.gov ↗
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Phase 1/2Carcinoma, Hepatocellular, Hepatocellular Cancer, Hepatocellular Carcinoma, Unresectable Hepatocellular Carcinoma, Liver Neoplasms …Recruiting
Est. primary completion 2027-10-18 · NCT07227012 · CT.gov ↗
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Phase 2Dedifferentiated Liposarcoma, Recurrent Dedifferentiated Liposarcoma, Recurrent Undifferentiated Pleomorphic Sarcoma …Active not recruiting
Est. primary completion 2027-10-31 · NCT03307616 · CT.gov ↗
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November 2027 (3)
Phase 2Head and Neck Squamous Cell CarcinomaRecruiting
Est. primary completion 2027-11 · NCT03406247 · CT.gov ↗
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Phase 1/2Carcinoma, Renal Cell, Advanced Renal Cell Carcinoma, Renal Cancer, Renal Neoplasm, Clear Cell Renal Cell Carcinoma …Recruiting
Est. primary completion 2027-11-02 · NCT07227415 · CT.gov ↗
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Phase 1Phase 1b, HC-7366, SHARK, Kidney CancerRecruiting
Est. primary completion 2027-11-30 · NCT07401875 · CT.gov ↗
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December 2027 (10)
Phase 2BRAF V600E, Colorectal Cancer, Sintilimab, MSS (Microsatellite Stable), Cetuximab, Dabrafenib, Ipilimumab N01Recruiting
Est. primary completion 2027-12 · NCT07506109 · CT.gov ↗
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Phase 2Cutaneous Melanoma, Stage III, Mucosal MelanomaRecruiting
Est. primary completion 2027-12 · NCT07230613 · CT.gov ↗
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Phase 1Kidney CancerActive not recruiting
Est. primary completion 2027-12-31 · NCT02950766 · CT.gov ↗
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Phase 1ALK Gene Rearrangement, EGFR Gene Mutation, Locally Advanced Lung Non-Small Cell Carcinoma, Lung Non-Small Cell Carcinoma …Active not recruiting
Est. primary completion 2027-12-31 · NCT04013542 · CT.gov ↗
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Phase 1/2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-12-31 · NCT06362369 · CT.gov ↗
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Phase 1/2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-12-31 · NCT02696993 · CT.gov ↗
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Phase 2Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Locally Advanced Bladder Carcinoma …Active not recruiting
Est. primary completion 2027-12-31 · NCT04940299 · CT.gov ↗
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Phase 2Brain Metastases, Renal Cell CarcinomaRecruiting
Est. primary completion 2027-12-31 · NCT05048212 · CT.gov ↗
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Phase 2Lymphoma, Non-Hodgkin, Multiple Myeloma, Advanced Solid TumorsRecruiting
Est. primary completion 2027-12-31 · NCT02693535 · CT.gov ↗
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Early phase / not applicableMetastatic MelanomaRecruiting
Est. primary completion 2027-12-31 · NCT07564570 · CT.gov ↗
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2028 (23)
January 2028 (2)
Phase 2Metastatic Melanoma, Skin CancerRecruiting
Est. primary completion 2028-01-01 · NCT05779423 · CT.gov ↗
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Phase 3Clear Cell Renal Cell Carcinoma, Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Neoplasm in the Lymph Nodes …Active not recruiting
Est. primary completion 2028-01-25 · NCT03793166 · CT.gov ↗
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March 2028 (4)
Phase 2Cutaneous Melanoma, Mucosal MelanomaRecruiting
Est. primary completion 2028-03 · NCT06999980 · CT.gov ↗
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Phase 2Hepato Cellular Carcinoma (HCC)Not yet recruiting
Est. primary completion 2028-03-17 · NCT07487662 · CT.gov ↗
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Phase 1Autoimmune Disease, Crohn Disease, Dermatomyositis, Hematopoietic and Lymphoid Cell Neoplasm, Inflammatory Bowel Disease …Recruiting
Est. primary completion 2028-03-30 · NCT03816345 · CT.gov ↗
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Phase 2Castration Levels of Testosterone, Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma, PSA Progression …Active not recruiting
Est. primary completion 2028-03-31 · NCT02703623 · CT.gov ↗
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May 2028 (1)
Phase 2MelanomaNot yet recruiting
Est. primary completion 2028-05-24 · NCT07511036 · CT.gov ↗
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June 2028 (3)
Phase 2Pancreatic Adenocarcinoma MetastaticRecruiting
Est. primary completion 2028-06 · NCT06747845 · CT.gov ↗
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Phase 2Metastatic Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8, Unresectable Renal Cell CarcinomaRecruiting
Est. primary completion 2028-06-15 · NCT05327686 · CT.gov ↗
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Phase 2Biliary Tract Cancers (BTC)Active not recruiting
Est. primary completion 2028-06-30 · NCT07654530 · CT.gov ↗
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July 2028 (2)
Phase 1/2Melanoma (Skin Cancer)Not yet recruiting
Est. primary completion 2028-07 · NCT07615881 · CT.gov ↗
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Phase 4Oncology, Infusion ReactionRecruiting
Est. primary completion 2028-07 · NCT06031233 · CT.gov ↗
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August 2028 (1)
Phase 1Advanced Clear Cell Renal Cell Carcinoma, Advanced Sarcomatoid Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma …Recruiting
Est. primary completion 2028-08-25 · NCT07128680 · CT.gov ↗
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October 2028 (1)
Early phase / not applicableMetastatic Renal Cell Carcinoma ( mRCC)Not yet recruiting
Est. primary completion 2028-10-01 · NCT07233668 · CT.gov ↗
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November 2028 (2)
Phase 2Melanoma Stage III, Melanoma Stage IV, Advanced Melanoma, MelanomaRecruiting
Est. primary completion 2028-11 · NCT06295159 · CT.gov ↗
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Early phase / not applicableMelanoma, Lung Cancer, Renal CancerRecruiting
Est. primary completion 2028-11-05 · NCT04605146 · CT.gov ↗
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December 2028 (7)
Phase 2Pancreatic CancerRecruiting
Est. primary completion 2028-12 · NCT06941857 · CT.gov ↗
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Phase 2Renal Cell Carcinoma, Clear CellActive not recruiting
Est. primary completion 2028-12-15 · NCT06708949 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2028-12-30 · NCT06492421 · CT.gov ↗
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Phase 2Hepatic Cancer, SurgeryRecruiting
Est. primary completion 2028-12-30 · NCT06492408 · CT.gov ↗
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Phase 2Lung Cancer, Inoperable DiseaseRecruiting
Est. primary completion 2028-12-30 · NCT06483347 · CT.gov ↗
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Phase 2Advanced RCCRecruiting
Est. primary completion 2028-12-31 · NCT07611825 · CT.gov ↗
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Phase 2Locally Advanced Gastric CancerNot yet recruiting
Est. primary completion 2028-12-31 · NCT07638631 · CT.gov ↗
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2029 (18)
March 2029 (4)
Phase 1Clear Cell Renal Cell Carcinoma, Solid TumorsRecruiting
Est. primary completion 2029-03 · NCT05536141 · CT.gov ↗
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Phase 2Melanoma (Skin Cancer), Melanoma Stage Stage IIIB, Melanoma Stage M1, Melanoma Stage IVRecruiting
Est. primary completion 2029-03 · NCT07740941 · CT.gov ↗
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Phase 1Fibrolamellar Hepatocellular Carcinoma (FLC)Recruiting
Est. primary completion 2029-03-01 · NCT04248569 · CT.gov ↗
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Phase 3Advanced Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage IV Hepatocellular Carcinoma AJCC v8Recruiting
Est. primary completion 2029-03-10 · NCT07166406 · CT.gov ↗
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April 2029 (1)
Phase 1Diffuse Pleural Mesothelioma, Gastroesophageal Carcinoma, Urothelial CarcinomaRecruiting
Est. primary completion 2029-04 · NCT07532902 · CT.gov ↗
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May 2029 (1)
Phase 2Metastatic Melanoma, Advanced MelanomaRecruiting
Est. primary completion 2029-05 · NCT07504796 · CT.gov ↗
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June 2029 (1)
Phase 1Uveal MelanomaRecruiting
Est. primary completion 2029-06-01 · NCT07501117 · CT.gov ↗
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July 2029 (2)
Phase 1/2MelanomaRecruiting
Est. primary completion 2029-07 · NCT06240143 · CT.gov ↗
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Phase 2Pancreatic CancerNot yet recruiting
Est. primary completion 2029-07-15 · NCT07683221 · CT.gov ↗
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August 2029 (1)
Phase 2CancerRecruiting
Est. primary completion 2029-08-25 · NCT03899155 · CT.gov ↗
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September 2029 (1)
Phase 1/2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2029-09 · NCT07563738 · CT.gov ↗
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October 2029 (2)
Phase 1/2Hepatocellular Carcinoma (HCC)Recruiting
Est. primary completion 2029-10-15 · NCT07291076 · CT.gov ↗
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Phase 1/2Lung Cancer, Liver Cancer, Colorectal Cancer, Pancreas Cancer, Ovary Cancer, Head and Neck Cancer, Breast Cancer, Gastric Cancer …Recruiting
Est. primary completion 2029-10-30 · NCT05187338 · CT.gov ↗
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November 2029 (3)
Phase 1/2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2029-11-02 · NCT04665206 · CT.gov ↗
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Phase 1/2Advanced Renal Cell Carcinoma (RCC)Recruiting
Est. primary completion 2029-11-28 · NCT07293351 · CT.gov ↗
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Phase 2Advanced Renal Cell Carcinoma (aRCC), Metastatic Renal Cell Carcinoma ( mRCC), Clear Cell Renal Cell Carcinoma (ccRCC)Recruiting
Est. primary completion 2029-11-30 · NCT07188896 · CT.gov ↗
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December 2029 (2)
Phase 2Renal Cell Carcinoma (Kidney Cancer), Immunotherapy, Molecular Targeted TherapyNot yet recruiting
Est. primary completion 2029-12 · NCT07715565 · CT.gov ↗
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Phase 2Nasopharyngeal Carcinoma (NPC), Metastatic Nasopharyngeal CarcinomaNot yet recruiting
Est. primary completion 2029-12-30 · NCT07756190 · CT.gov ↗
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2030 (12)
January 2030 (1)
Phase 2/3Metastatic Uveal MelanomaRecruiting
Est. primary completion 2030-01 · NCT06581406 · CT.gov ↗
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March 2030 (1)
Phase 2Lung Cancer - Non Small CellRecruiting
Est. primary completion 2030-03-31 · NCT06926790 · CT.gov ↗
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May 2030 (1)
Phase 1Renal Cell CarcinomaRecruiting
Est. primary completion 2030-05-03 · NCT07195682 · CT.gov ↗
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June 2030 (2)
Phase 1Neuroendocrine Carcinoma, Neuroendocrine TumorsRecruiting
Est. primary completion 2030-06-01 · NCT06889493 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2030-06-25 · NCT07603856 · CT.gov ↗
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August 2030 (1)
Phase 1/2MelanomaRecruiting
Est. primary completion 2030-08-16 · NCT06683755 · CT.gov ↗
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September 2030 (3)
Phase 1Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC))Not yet recruiting
Est. primary completion 2030-09 · NCT07430202 · CT.gov ↗
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Phase 1/2Triple-Negative Breast Cancer (TNBC)Not yet recruiting
Est. primary completion 2030-09 · NCT07762703 · CT.gov ↗
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Phase 1/2Glioblastoma (GBM)Not yet recruiting
Est. primary completion 2030-09 · NCT07762716 · CT.gov ↗
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December 2030 (3)
Phase 2/3Lung Adenocarcinoma, Lung Adenosquamous Carcinoma, Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8 …Active not recruiting
Est. primary completion 2030-12-12 · NCT04929041 · CT.gov ↗
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Phase 2Liver Cancer, AntibodyRecruiting
Est. primary completion 2030-12-30 · NCT06482801 · CT.gov ↗
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Phase 1/2Advanced Soft Tissue Sarcoma, Metastatic Soft Tissue SarcomaRecruiting
Est. primary completion 2030-12-31 · NCT03138161 · CT.gov ↗
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2031 (7)
January 2031 (1)
Phase 2Breast CancerRecruiting
Est. primary completion 2031-01-01 · NCT03815890 · CT.gov ↗
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August 2031 (1)
Phase 1/2Locally Advanced Clear Cell Renal Cell Carcinoma, Locally Advanced Sarcomatoid Renal Cell Carcinoma …Recruiting
Est. primary completion 2031-08-01 · NCT06866262 · CT.gov ↗
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October 2031 (1)
Phase 2Hepatocellular Carcinoma (HCC)Recruiting
Est. primary completion 2031-10-31 · NCT07689175 · CT.gov ↗
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December 2031 (4)
Phase 3Advanced Kidney CancerNot yet recruiting
Est. primary completion 2031-12 · NCT07338981 · CT.gov ↗
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Phase 1Soft Tissue SarcomasRecruiting
Est. primary completion 2031-12-31 · NCT07444619 · CT.gov ↗
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Phase 2Colorectal Cancer (MSI-H)Not yet recruiting
Est. primary completion 2031-12-31 · NCT07403877 · CT.gov ↗
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Phase 2/3Resectable Gastric/Gastroesophageal Junction AdenocarcinomaRecruiting
Est. primary completion 2031-12-31 · NCT07643623 · CT.gov ↗
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2032 (6)
February 2032 (1)
Phase 1/2Advanced Solid TumorsRecruiting
Est. primary completion 2032-02-18 · NCT05533697 · CT.gov ↗
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March 2032 (1)
Phase 2Colon CarcinomaRecruiting
Est. primary completion 2032-03-01 · NCT03026140 · CT.gov ↗
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April 2032 (1)
Phase 3Malignant Melanoma Stage IIIRecruiting
Est. primary completion 2032-04-15 · NCT06794775 · CT.gov ↗
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May 2032 (1)
Phase 3Metastatic Kidney Cancer, Metastatic Kidney CarcinomaRecruiting
Est. primary completion 2032-05-05 · NCT06364631 · CT.gov ↗
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July 2032 (2)
Phase 2Endometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Dedifferentiated Carcinoma …Recruiting
Est. primary completion 2032-07-30 · NCT05112601 · CT.gov ↗
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Phase 1/2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2032-07-31 · NCT07355205 · CT.gov ↗
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2033 (3)
January 2033 (1)
Phase 3Advanced Clear Cell Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8 …Recruiting
Est. primary completion 2033-01-31 · NCT07383441 · CT.gov ↗
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June 2033 (1)
Phase 2/3Stage III Cutaneous Melanoma AJCC v7, Stage IV Cutaneous Melanoma AJCC v6 and v7Active not recruiting
Est. primary completion 2033-06-30 · NCT02339571 · CT.gov ↗
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August 2033 (1)
Phase 2Advanced Clear Cell Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8 …Recruiting
Est. primary completion 2033-08-01 · NCT07510334 · CT.gov ↗
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2038 (1)
August 2038 (1)
Phase 2MelanomaNot yet recruiting
Est. primary completion 2038-08 · NCT02498756 · CT.gov ↗
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2040 (1)
February 2040 (1)
Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2040-02-28 · NCT07770100 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (60)
Phase 2/3 (10)
Phase 2 (364)
Phase 1/2 (127)
Phase 1 (216)
Phase 4 (6)
Early phase / not applicable (13)
Used as active comparator (18)
Appears in other studies (12)