Asset profile

Telisotuzumab Adizutecan

Antibody–drug conjugate

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Phase 3underway

Evidence outlook · registrational

Non-Small Cell Lung Cancer: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2030-09.

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Competitive landscape

73 competitors in this universe: 13 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 58 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Telisotuzumab Adizutecan: this drugPhase 3Antibody–drug conjugateMET
CapmatinibApprovedSmall moleculeMET
Telisotuzumab VedotinApprovedAntibody–drug conjugateMET
Tepotinib (Tepmetko)ApprovedSmall moleculeMET
ASKC202Phase 3Small moleculeMET
GlumetinibPhase 3Small moleculeMET
Savolitinib (Orpathys)Phase 3Small moleculeMET
VebreltinibPhase 3Small moleculeMET
ABBV-400Phase 2Antibody–drug conjugateMET
RC108Phase 2Antibody–drug conjugateMET
CKD-703Phase 1/2Antibody–drug conjugateMET
REGN5093Phase 1/2Monoclonal antibodyMET
VERT-002Phase 1/2Monoclonal antibodyMET
DO-2Phase 1Small moleculeMET
Afatinib (Gilotrif)ApprovedSmall moleculeEGFR/HER1, HER2, HER4
Alectinib (Alecensa)ApprovedSmall moleculeALK

…and 58 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(15 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (4)
July 2027 (1)
Phase 1Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-07 · NCT05005403 · CT.gov ↗
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August 2027 (1)
Phase 2Metastatic Colorectal CancerActive not recruiting
Est. primary completion 2027-08 · NCT06614192 · CT.gov ↗
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November 2027 (1)
Phase 1/2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-11 · NCT06772623 · CT.gov ↗
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December 2027 (1)
Phase 1Colorectal CancerActive not recruiting
Est. primary completion 2027-12 · NCT06464692 · CT.gov ↗
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2028 (2)
March 2028 (1)
Phase 2Metastatic Colorectal CancerRecruiting
Est. primary completion 2028-03 · NCT06820463 · CT.gov ↗
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September 2028 (1)
Phase 2Pancreatobiliary Cancers, Pancreatic Ductal AdenocarcinomaRecruiting
Est. primary completion 2028-09 · NCT07769502 · CT.gov ↗
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2029 (3)
May 2029 (1)
Phase 3Colorectal CancerRecruiting
Est. primary completion 2029-05 · NCT07525206 · CT.gov ↗
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October 2029 (1)
Phase 2Head and Neck Squamous Cell CarcinomaRecruiting
Est. primary completion 2029-10 · NCT07744126 · CT.gov ↗
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November 2029 (1)
Phase 2Colorectal CancerRecruiting
Est. primary completion 2029-11 · NCT07023289 · CT.gov ↗
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2030 (3)
September 2030 (1)
Phase 2/3Non-Small Cell Lung CancerRecruiting
Est. primary completion 2030-09 · NCT07155187 · CT.gov ↗
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October 2030 (1)
Phase 2Locally Advanced Unresectable or Metastatic Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Esophageal AdenocarcinomaActive not recruiting
Est. primary completion 2030-10 · NCT06628310 · CT.gov ↗
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December 2030 (1)
Phase 2Solid Tumors Harboring MET AmplificationRecruiting
Est. primary completion 2030-12 · NCT07196644 · CT.gov ↗
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2031 (3)
April 2031 (1)
Phase 3Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2031-04 · NCT07821684 · CT.gov ↗
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June 2031 (1)
Phase 2/3Metastatic Pancreatic Ductal Adenocarcinoma, PDACRecruiting
Est. primary completion 2031-06 · NCT07490301 · CT.gov ↗
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December 2031 (1)
Phase 2/3Non-Small Cell Lung CancerRecruiting
Est. primary completion 2031-12 · NCT07005102 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (2)
Phase 2/3 (3)
Phase 2 (7)
Phase 1/2 (1)
Phase 1 (2)