Asset profile

Durvalumab

Monoclonal antibody

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Approvedregulatory verdict

Evidence outlook

Approved: Non-Small Cell Lung Cancer

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Reliable signal

How the evidence outlook works ↗

Competitive landscape

71 competitors in this universe: 10 direct rivals (same mechanism and indication), 1 same-class, 60 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Durvalumab: this drugApprovedMonoclonal antibodyPD-L1
AtezolizumabApprovedMonoclonal antibodyPD-L1
Tecentriq Hybreza (atezolizumab And Hyaluronidase-Tqjs)ApprovedMonoclonal antibodyPD-L1
AdebrelimabPhase 3Monoclonal antibodyPD-L1
CS1001 Monoclonal AntibodyPhase 3Monoclonal antibodyPD-L1
EnvafolimabPhase 3Monoclonal antibodyPD-L1
KL-A167Phase 3Monoclonal antibodyPD-L1
PF-08046054Phase 3Antibody–drug conjugatePD-L1
HLX43Phase 2/3Antibody–drug conjugatePD-L1
177Lu-RAD204Phase 1RadiopharmaceuticalPD-L1
BPI-371153Phase 1Small moleculePD-L1
IBC-Ab002Phase 1Monoclonal antibodyPD-L1
Afatinib (Gilotrif)ApprovedSmall moleculeEGFR/HER1, HER2, HER4
Alectinib (Alecensa)ApprovedSmall moleculeALK
Alymsys (bevacizumab-Maly)ApprovedMonoclonal antibodyVEGF-A
AmivantamabApprovedMultispecific antibodyEGFR x c-MET

…and 56 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(215 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (36)
October 2026 (6)
Phase 2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2026-10-23 · NCT06008093 · CT.gov ↗
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Phase 1Advanced Solid TumorRecruiting
Est. primary completion 2026-10-30 · NCT06302426 · CT.gov ↗
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Phase 2Pancreatic Ductal AdenocarcinomaRecruiting
Est. primary completion 2026-10-30 · NCT06060405 · CT.gov ↗
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Phase 2Gallbladder Cancer UnresectableRecruiting
Est. primary completion 2026-10-30 · NCT06591650 · CT.gov ↗
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Early phase / not applicableBiliary Tract Cancers (BTC)Recruiting
Est. primary completion 2026-10-30 · NCT06611345 · CT.gov ↗
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Phase 2Bladder CancerActive not recruiting
Est. primary completion 2026-10-31 · NCT03768570 · CT.gov ↗
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November 2026 (7)
Phase 1/2Esophageal Adenocarcinoma, Gastroesophageal Junction AdenocarcinomaActive not recruiting
Est. primary completion 2026-11 · NCT02962063 · CT.gov ↗
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Phase 2Small Cell Lung Cancer Extensive StageActive not recruiting
Est. primary completion 2026-11 · NCT05856695 · CT.gov ↗
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Phase 2Germ Cell Tumor, Nonseminomatous Germ Cell Tumor, Seminoma, Germinomatous Germ Cell Tumor, Dysgerminoma, Pineal Germ Cell TumorActive not recruiting
Est. primary completion 2026-11 · NCT03158064 · CT.gov ↗
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Phase 2Advanced Hepatocellular Carcinoma, Metastatic Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8 …Recruiting
Est. primary completion 2026-11-13 · NCT07174570 · CT.gov ↗
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Phase 1Locally Advanced Intrahepatic Cholangiocarcinoma, Oligometastatic Intrahepatic Cholangiocarcinoma …Recruiting
Est. primary completion 2026-11-30 · NCT06058663 · CT.gov ↗
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Phase 2Hepatocellular CarcinomaActive not recruiting
Est. primary completion 2026-11-30 · NCT07081633 · CT.gov ↗
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Phase 2Gastrointestinal Neuroendocrine CarcinomaRecruiting
Est. primary completion 2026-11-30 · NCT06070740 · CT.gov ↗
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December 2026 (23)
Phase 1Breast CancerActive not recruiting
Est. primary completion 2026-12 · NCT02826434 · CT.gov ↗
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Phase 1Solid Tumor, Advanced Cancer, Metastatic Cancer, Gastric Cancer, Gastroesophageal Junction Carcinoma, Esophageal Adenocarcinoma …Recruiting
Est. primary completion 2026-12 · NCT04900818 · CT.gov ↗
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Phase 1/2Metastatic Pancreatic CancerActive not recruiting
Est. primary completion 2026-12 · NCT05927142 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2026-12 · NCT05000710 · CT.gov ↗
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Phase 2Breast Neoplasm, Triple Negative Breast Cancer (TNBC), HRDRecruiting
Est. primary completion 2026-12 · NCT03740893 · CT.gov ↗
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Phase 2Stomach Cancer, AdenocarcinomaRecruiting
Est. primary completion 2026-12 · NCT05620628 · CT.gov ↗
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Phase 3Oropharyngeal CancerActive not recruiting
Est. primary completion 2026-12 · NCT04116047 · CT.gov ↗
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Phase 3Non-Small Cell Lung CancerRecruiting
Est. primary completion 2026-12 · NCT04585490 · CT.gov ↗
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Phase 2Bile Duct Cancer, Cholangiocarcinoma, Cholangiocarcinoma Non-resectable, Cholangiocarcinoma Metastatic …Recruiting
Est. primary completion 2026-12-01 · NCT05655949 · CT.gov ↗
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Phase 4Non-Small Cell Lung CancerRecruiting
Est. primary completion 2026-12-17 · NCT06908070 · CT.gov ↗
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Phase 2Biliary Tract CancerActive not recruiting
Est. primary completion 2026-12-30 · NCT06490107 · CT.gov ↗
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Phase 2Anatomic Stage IV Breast Cancer AJCC v8, Invasive Breast Carcinoma, Metastatic Triple-Negative Breast CarcinomaRecruiting
Est. primary completion 2026-12-30 · NCT03606967 · CT.gov ↗
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Phase 1Locally Advanced Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8 …Recruiting
Est. primary completion 2026-12-31 · NCT05136846 · CT.gov ↗
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Phase 1Solid Tumor, AdultRecruiting
Est. primary completion 2026-12-31 · NCT03772561 · CT.gov ↗
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Phase 1Primary Central Nervous System LymphomaActive not recruiting
Est. primary completion 2026-12-31 · NCT04462328 · CT.gov ↗
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Phase 2Hepatocellular CarcinomaRecruiting
Est. primary completion 2026-12-31 · NCT05844046 · CT.gov ↗
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Phase 2Pulmonary Large-cell Neuroendocrine CarcinomaRecruiting
Est. primary completion 2026-12-31 · NCT06418087 · CT.gov ↗
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Phase 2Ovarian CancerRecruiting
Est. primary completion 2026-12-31 · NCT04918186 · CT.gov ↗
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Phase 2Small Cell Lung Cancer Limited StageActive not recruiting
Est. primary completion 2026-12-31 · NCT04602533 · CT.gov ↗
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Phase 2Anal Cancer, Anal Carcinoma, Anal Cancer Stage III, Anal Cancer Stage IIActive not recruiting
Est. primary completion 2026-12-31 · NCT04230759 · CT.gov ↗
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Phase 2Hepatocellular CarcinomaRecruiting
Est. primary completion 2026-12-31 · NCT06698250 · CT.gov ↗
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Phase 2Hepatocellular Cancer, Hepatocellular Carcinoma, Metastatic Hepatocellular CarcinomaActive not recruiting
Est. primary completion 2026-12-31 · NCT03937830 · CT.gov ↗
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Phase 3CancerEnrolling by invitation
Est. primary completion 2026-12-31 · NCT05303532 · CT.gov ↗
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2027 (80)
January 2027 (10)
Phase 1Solid Tumor, Adult, Malignant Solid Tumor, Stomach Adenocarcinoma, Esophageal AdenocarcinomaRecruiting
Est. primary completion 2027-01 · NCT06824363 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-01 · NCT05206812 · CT.gov ↗
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Phase 2Extrahepatic Cholangiocarcinoma, Unresectable Perihilar or Ductal CCARecruiting
Est. primary completion 2027-01 · NCT06440993 · CT.gov ↗
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Phase 2Extensive Stage Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-01 · NCT04699838 · CT.gov ↗
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Phase 2Mismatch Repair Proficient Colorectal Cancer, Pancreatic Adenocarcinoma, LeiomyosarcomaActive not recruiting
Est. primary completion 2027-01-01 · NCT03851614 · CT.gov ↗
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Phase 2Biliary Tract Neoplasms ImmunotherapyRecruiting
Est. primary completion 2027-01-01 · NCT07679399 · CT.gov ↗
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Phase 2Esophagus AdenocarcinomaActive not recruiting
Est. primary completion 2027-01-01 · NCT05713838 · CT.gov ↗
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Phase 2Muscle Invasive Bladder Urothelial Carcinoma, Stage II Bladder Cancer AJCC v8, Stage IIIA Bladder Cancer AJCC v8Not yet recruiting
Est. primary completion 2027-01-01 · NCT07332351 · CT.gov ↗
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Phase 2Lung CancerActive not recruiting
Est. primary completion 2027-01-18 · NCT05374603 · CT.gov ↗
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Phase 2Bladder Urothelial Carcinoma, Stage IV Bladder Cancer AJCC v8, Stage IVA Bladder Cancer AJCC v8, Stage IVB Bladder Cancer AJCC v8Active not recruiting
Est. primary completion 2027-01-31 · NCT03601455 · CT.gov ↗
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February 2027 (6)
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-02 · NCT06463665 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-02 · NCT04716946 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-02 · NCT04499053 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-02 · NCT05696782 · CT.gov ↗
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Phase 2Chronic Lymphocytic Leukemia, Richter Syndrome, Small Lymphocytic LymphomaRecruiting
Est. primary completion 2027-02-22 · NCT05388006 · CT.gov ↗
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Phase 1BCLC Stage B Hepatocellular Carcinoma, BCLC Stage C Hepatocellular Carcinoma, Locally Advanced Hepatocellular Carcinoma …Active not recruiting
Est. primary completion 2027-02-23 · NCT04605731 · CT.gov ↗
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March 2027 (5)
Phase 2Extensive-stage Small-cell Lung CancerRecruiting
Est. primary completion 2027-03 · NCT06223711 · CT.gov ↗
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Phase 1Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-03-01 · NCT03983954 · CT.gov ↗
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Phase 1/2Bladder CancerRecruiting
Est. primary completion 2027-03-30 · NCT04106115 · CT.gov ↗
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Phase 2Intrahepatic CholangiocarcinomaRecruiting
Est. primary completion 2027-03-30 · NCT05422690 · CT.gov ↗
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Phase 1Advanced Malignant Skin Neoplasm, Metastatic Malignant Skin NeoplasmActive not recruiting
Est. primary completion 2027-03-31 · NCT04387084 · CT.gov ↗
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April 2027 (1)
Phase 2Advanced Unresectable Hepatocellular CarcinomaRecruiting
Est. primary completion 2027-04 · NCT07175441 · CT.gov ↗
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May 2027 (7)
Phase 1/2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-05 · NCT03694236 · CT.gov ↗
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Phase 2Combined Hepatocellular and CholangiocarcinomaNot yet recruiting
Est. primary completion 2027-05 · NCT06855225 · CT.gov ↗
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Phase 2Colorectal Cancer, Resectable Colorectal CarcinomaRecruiting
Est. primary completion 2027-05 · NCT05845450 · CT.gov ↗
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Phase 2Intrahepatic CholangiocarcinomaRecruiting
Est. primary completion 2027-05 · NCT06375915 · CT.gov ↗
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Phase 1/2Metastatic Biliary Tract CancerRecruiting
Est. primary completion 2027-05-01 · NCT06548412 · CT.gov ↗
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Phase 2Gastric CancerActive not recruiting
Est. primary completion 2027-05-04 · NCT04379596 · CT.gov ↗
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Phase 1/2Lung CancerRecruiting
Est. primary completion 2027-05-30 · NCT05886439 · CT.gov ↗
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June 2027 (12)
Phase 1Gastroesophageal AdenocarcinomaRecruiting
Est. primary completion 2027-06 · NCT05733689 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-06 · NCT05742607 · CT.gov ↗
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Phase 2Hepatocellular CarcinomaActive not recruiting
Est. primary completion 2027-06 · NCT05063565 · CT.gov ↗
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Phase 1Advanced Hepatocellular CarcinomaRecruiting
Est. primary completion 2027-06-01 · NCT06470256 · CT.gov ↗
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Phase 1Borderline Resectable Pancreatic Ductal Adenocarcinoma, Locally Advanced Cholangiocarcinoma, Locally Advanced Pancreatic Adenocarcinoma …Recruiting
Est. primary completion 2027-06-01 · NCT07619313 · CT.gov ↗
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Phase 2Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid NeoplasmRecruiting
Est. primary completion 2027-06-01 · NCT03907475 · CT.gov ↗
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Early phase / not applicableHepatocellular CarcinomaRecruiting
Est. primary completion 2027-06-25 · NCT06796114 · CT.gov ↗
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Phase 1Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-06-30 · NCT04686305 · CT.gov ↗
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Phase 2Biliary Tract CancerNot yet recruiting
Est. primary completion 2027-06-30 · NCT06502080 · CT.gov ↗
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Phase 2Metastatic Angiosarcoma, Metastatic Dedifferentiated Liposarcoma, Metastatic Osteosarcoma, Recurrent Angiosarcoma …Active not recruiting
Est. primary completion 2027-06-30 · NCT04668300 · CT.gov ↗
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Phase 2Lung Adenocarcinoma, Lung Large Cell Carcinoma, Lung Non-Squamous Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8Active not recruiting
Est. primary completion 2027-06-30 · NCT05198830 · CT.gov ↗
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Phase 3Esophageal Squamous Cell CarcinomaActive not recruiting
Est. primary completion 2027-06-30 · NCT04550260 · CT.gov ↗
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July 2027 (7)
Phase 2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-07 · NCT03999710 · CT.gov ↗
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Phase 2Intrahepatic Cholangiocarcinoma, FGFR2 Gene Rearrangement, FGFR2 Gene MutationRecruiting
Est. primary completion 2027-07 · NCT06728410 · CT.gov ↗
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Phase 3Extensive-Stage Small-Cell Lung Cancer, Small-Cell Lung CancerActive not recruiting
Est. primary completion 2027-07-05 · NCT06211036 · CT.gov ↗
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Phase 3Breast CancerRecruiting
Est. primary completion 2027-07-28 · NCT06103864 · CT.gov ↗
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Phase 2Esophageal CancerRecruiting
Est. primary completion 2027-07-31 · NCT06290505 · CT.gov ↗
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Phase 2Hepatocellular Carcinoma Non-resectable, HCCActive not recruiting
Est. primary completion 2027-07-31 · NCT04522544 · CT.gov ↗
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Phase 2Bladder Urothelial Carcinoma, Muscle Invasive Bladder Carcinoma, Stage II Bladder Cancer AJCC v8, Stage IIIA Bladder Cancer AJCC v8Recruiting
Est. primary completion 2027-07-31 · NCT06263153 · CT.gov ↗
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August 2027 (4)
Phase 2Locally Advanced Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage IV Hepatocellular Carcinoma AJCC v8 …Not yet recruiting
Est. primary completion 2027-08-01 · NCT07511504 · CT.gov ↗
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Phase 2ImmunotherapyActive not recruiting
Est. primary completion 2027-08-10 · NCT04169841 · CT.gov ↗
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Phase 1Solid TumoursRecruiting
Est. primary completion 2027-08-30 · NCT07391670 · CT.gov ↗
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Phase 3Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2027-08-31 · NCT04465968 · CT.gov ↗
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September 2027 (6)
Phase 2Cancer, Tumors, Neoplasm, NeoplasiaRecruiting
Est. primary completion 2027-09 · NCT02925234 · CT.gov ↗
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Phase 3Breast CancerActive not recruiting
Est. primary completion 2027-09-20 · NCT05629585 · CT.gov ↗
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Phase 2HCC - Hepatocellular CarcinomaActive not recruiting
Est. primary completion 2027-09-27 · NCT06045975 · CT.gov ↗
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Phase 2Extensive-stage Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-09-30 · NCT04397003 · CT.gov ↗
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Phase 2Extensive-Stage Small-Cell Lung CancerActive not recruiting
Est. primary completion 2027-09-30 · NCT05796089 · CT.gov ↗
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Phase 2/3Renal Pelvis and Ureter Urothelial CarcinomaRecruiting
Est. primary completion 2027-09-30 · NCT04628767 · CT.gov ↗
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October 2027 (6)
Phase 2Small-cell Lung Cancer, Extensive-stage Small-cell Lung Cancer, Lung CancerRecruiting
Est. primary completion 2027-10-01 · NCT05068232 · CT.gov ↗
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Phase 2Hepatocellular Carcinoma, Cirrhosis, LiverRecruiting
Est. primary completion 2027-10-01 · NCT06526104 · CT.gov ↗
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Early phase / not applicableNon-Small Cell Lung CancerRecruiting
Est. primary completion 2027-10-01 · NCT06484491 · CT.gov ↗
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Phase 3Hepatocellular Carcinoma (HCC)Recruiting
Est. primary completion 2027-10-12 · NCT07027436 · CT.gov ↗
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Phase 1/2Colorectal Neoplasms, Breast NeoplasmsActive not recruiting
Est. primary completion 2027-10-30 · NCT02484404 · CT.gov ↗
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Phase 2Borderline Resectable Pancreatic Adenocarcinoma, Resectable Pancreatic Adenocarcinoma, Stage IA Pancreatic Cancer AJCC v8 …Active not recruiting
Est. primary completion 2027-10-30 · NCT04940286 · CT.gov ↗
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November 2027 (1)
Phase 3Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2027-11-01 · NCT05687266 · CT.gov ↗
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December 2027 (15)
Phase 1Hepatocellular CarcinomaActive not recruiting
Est. primary completion 2027-12 · NCT06710223 · CT.gov ↗
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Phase 1Biliary Tract Cancer, CholangiocarcinomaRecruiting
Est. primary completion 2027-12 · NCT06546969 · CT.gov ↗
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Phase 2Triple Negative Breast Cancer MetastaticRecruiting
Est. primary completion 2027-12 · NCT05582538 · CT.gov ↗
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Phase 2Extensive Stage Lung Small Cell CancerNot yet recruiting
Est. primary completion 2027-12 · NCT07172412 · CT.gov ↗
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Phase 2Small Cell Lung Cancer, Lung CancerActive not recruiting
Est. primary completion 2027-12 · NCT04472949 · CT.gov ↗
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Phase 2Invasive Breast Cancer, Inflammatory Breast Cancer Stage III, HER2-positive Breast Cancer, HER2 Low Breast Adenocarcinoma, Breast CancerRecruiting
Est. primary completion 2027-12-01 · NCT05795101 · CT.gov ↗
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Phase 2Hepatocellular Carcinoma, Biliary Tract CancerRecruiting
Est. primary completion 2027-12-01 · NCT05733598 · CT.gov ↗
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Phase 2Non-muscle Invasive Bladder Cancer, Non-Muscle Invasive Bladder Urothelial CarcinomaRecruiting
Est. primary completion 2027-12-22 · NCT06503614 · CT.gov ↗
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Phase 1Hydronephrosis, Infiltrating Bladder Urothelial Carcinoma Sarcomatoid Variant, Infiltrating Bladder Urothelial Carcinoma …Active not recruiting
Est. primary completion 2027-12-31 · NCT02812420 · CT.gov ↗
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Phase 1/2Stage III Fallopian Tube Cancer AJCC v7, Stage III Ovarian Cancer AJCC v6 and v7, Stage III Primary Peritoneal Cancer AJCC v7 …Active not recruiting
Est. primary completion 2027-12-31 · NCT02726997 · CT.gov ↗
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Phase 1/2Extensive Stage Lung Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8Active not recruiting
Est. primary completion 2027-12-31 · NCT04728230 · CT.gov ↗
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Phase 2Rare TumourNot yet recruiting
Est. primary completion 2027-12-31 · NCT06692491 · CT.gov ↗
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Phase 2Lung CancerRecruiting
Est. primary completion 2027-12-31 · NCT05632809 · CT.gov ↗
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Phase 2Locally Advanced Ampulla of Vater Carcinoma, Locally Advanced Biliary Tract Carcinoma, Locally Advanced Extrahepatic Cholangiocarcinoma …Recruiting
Est. primary completion 2027-12-31 · NCT07780838 · CT.gov ↗
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Early phase / not applicableExtrahepatic CholangiocarcinomaRecruiting
Est. primary completion 2027-12-31 · NCT07235007 · CT.gov ↗
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2028 (48)
January 2028 (6)
Phase 2Malignant Solid NeoplasmsRecruiting
Est. primary completion 2028-01 · NCT02029001 · CT.gov ↗
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Phase 2Epithelial Ovarian CancerRecruiting
Est. primary completion 2028-01 · NCT04644289 · CT.gov ↗
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Phase 2Adenocarcinoma of Lung, Lung CancerRecruiting
Est. primary completion 2028-01 · NCT04105270 · CT.gov ↗
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Phase 2Extrapulmonary Small Cell CarcinomaRecruiting
Est. primary completion 2028-01-01 · NCT06464068 · CT.gov ↗
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Phase 2Hepatocellular CarcinomaRecruiting
Est. primary completion 2028-01-31 · NCT06880523 · CT.gov ↗
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Phase 2Extensive-stage Small-cell Lung CancerRecruiting
Est. primary completion 2028-01-31 · NCT07459634 · CT.gov ↗
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February 2028 (3)
Phase 2Triple Negative Breast CancerRecruiting
Est. primary completion 2028-02 · NCT06954480 · CT.gov ↗
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Phase 2Hepatocellular Carcinoma, Liver CancerNot yet recruiting
Est. primary completion 2028-02 · NCT07226063 · CT.gov ↗
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Phase 2Small Cell Lung CarcinomaActive not recruiting
Est. primary completion 2028-02-24 · NCT05617963 · CT.gov ↗
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March 2028 (4)
Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2028-03-01 · NCT07653438 · CT.gov ↗
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Phase 1/2Hepatocellular Carcinoma (HCC), Unresectable Hepatocellular CarcinomaRecruiting
Est. primary completion 2028-03-31 · NCT06911255 · CT.gov ↗
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Phase 2Gastric Adenocarcinoma, Gastroesophageal Junction AdenocarcinomaActive not recruiting
Est. primary completion 2028-03-31 · NCT05034887 · CT.gov ↗
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Phase 2Clear Cell Renal Cell Carcinoma, Locally Advanced Pancreatic Cancer, Locally Advanced Malignant Solid Neoplasm …Active not recruiting
Est. primary completion 2028-03-31 · NCT03682289 · CT.gov ↗
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April 2028 (2)
Phase 1Bladder CancerRecruiting
Est. primary completion 2028-04 · NCT06963346 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2028-04 · NCT07146230 · CT.gov ↗
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May 2028 (2)
Phase 1Small Cell Lung CancerRecruiting
Est. primary completion 2028-05-21 · NCT07531095 · CT.gov ↗
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Phase 1/2MesotheliomaRecruiting
Est. primary completion 2028-05-31 · NCT05932199 · CT.gov ↗
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June 2028 (3)
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2028-06 · NCT06680050 · CT.gov ↗
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Phase 1/2Gastric Cancer, Esophageal Adenocarcinoma, Hepatocellular Carcinoma, Colorectal CancerRecruiting
Est. primary completion 2028-06-30 · NCT03539822 · CT.gov ↗
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Phase 3Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8Active not recruiting
Est. primary completion 2028-06-30 · NCT06732401 · CT.gov ↗
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July 2028 (3)
Phase 4Oncology, Infusion ReactionRecruiting
Est. primary completion 2028-07 · NCT06031233 · CT.gov ↗
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Phase 2CholangiocarcinomaRecruiting
Est. primary completion 2028-07-01 · NCT07673341 · CT.gov ↗
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Phase 2Advanced Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage IIIA Hepatocellular Carcinoma AJCC v8 …Recruiting
Est. primary completion 2028-07-31 · NCT04430452 · CT.gov ↗
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August 2028 (1)
Phase 2Urothelial Carcinoma, Bladder CancerActive not recruiting
Est. primary completion 2028-08-31 · NCT05137262 · CT.gov ↗
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September 2028 (3)
Phase 2Resectable Gasrtic CancerNot yet recruiting
Est. primary completion 2028-09 · NCT07757191 · CT.gov ↗
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Phase 2Large Cell Neuroendocrine Carcinoma of the LungRecruiting
Est. primary completion 2028-09 · NCT06393816 · CT.gov ↗
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Phase 1/2Fibrolamellar Hepatocellular CarcinomaRecruiting
Est. primary completion 2028-09-01 · NCT06027086 · CT.gov ↗
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October 2028 (5)
Phase 2Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8Recruiting
Est. primary completion 2028-10-08 · NCT07288034 · CT.gov ↗
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Phase 1NeoplasmsRecruiting
Est. primary completion 2028-10-16 · NCT06551142 · CT.gov ↗
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Phase 2Stomach NeoplasmsRecruiting
Est. primary completion 2028-10-30 · NCT06630130 · CT.gov ↗
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Phase 3Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2028-10-31 · NCT03833154 · CT.gov ↗
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Phase 3Urinary Bladder Neoplasms, Immune Checkpoint Inhibitors, Methotrexate, Vinblastine, Doxorubicin, Cisplatin, GemcitabineRecruiting
Est. primary completion 2028-10-31 · NCT06960577 · CT.gov ↗
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November 2028 (5)
Phase 2Advanced Biliary Tract CarcinomaRecruiting
Est. primary completion 2028-11 · NCT07036380 · CT.gov ↗
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Phase 2Advanced Intrahepatic CholangiocarcinomaRecruiting
Est. primary completion 2028-11-19 · NCT06858735 · CT.gov ↗
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Phase 3Breast CancerActive not recruiting
Est. primary completion 2028-11-20 · NCT06112379 · CT.gov ↗
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Phase 3Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2028-11-30 · NCT01993810 · CT.gov ↗
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Phase 3Advanced or Recurrent Endometrial CancerActive not recruiting
Est. primary completion 2028-11-30 · NCT06746116 · CT.gov ↗
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December 2028 (11)
Phase 3Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2028-12 · NCT04597671 · CT.gov ↗
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Phase 3Biliary Tract CancerRecruiting
Est. primary completion 2028-12-01 · NCT06282575 · CT.gov ↗
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Phase 3Extensive-stage Small Cell Lung CancerNot yet recruiting
Est. primary completion 2028-12-16 · NCT06719336 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2028-12-30 · NCT06492421 · CT.gov ↗
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Phase 2Hepatic Cancer, SurgeryRecruiting
Est. primary completion 2028-12-30 · NCT06492408 · CT.gov ↗
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Phase 2Lung Cancer, Inoperable DiseaseRecruiting
Est. primary completion 2028-12-30 · NCT06483347 · CT.gov ↗
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Phase 1/2Urothelial Carcinoma, Bladder CancerActive not recruiting
Est. primary completion 2028-12-31 · NCT03317158 · CT.gov ↗
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Phase 2Extensive Stage Lung Small Cell Carcinoma, Lung Small Cell Carcinoma, A Subtype, Lung Small Cell Carcinoma, I Subtype …Recruiting
Est. primary completion 2028-12-31 · NCT06769126 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2028-12-31 · NCT06667908 · CT.gov ↗
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Phase 2HCCActive not recruiting
Est. primary completion 2028-12-31 · NCT04988945 · CT.gov ↗
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Phase 3Recurrent Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8 …Active not recruiting
Est. primary completion 2028-12-31 · NCT04092283 · CT.gov ↗
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2029 (24)
January 2029 (1)
Phase 3Small-cell Lung Cancer, Extensive Stage Small-cell Lung CancerActive not recruiting
Est. primary completion 2029-01-04 · NCT07005128 · CT.gov ↗
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February 2029 (2)
Phase 2Small Cell Lung Cancer (SCLC)Recruiting
Est. primary completion 2029-02 · NCT07149363 · CT.gov ↗
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Phase 2Small Cell Lung Cancer ( SCLC ), Extensive Stage Small Cell Lung Cancer (ES-SCLC)Recruiting
Est. primary completion 2029-02-01 · NCT07339059 · CT.gov ↗
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March 2029 (2)
Phase 1Biliary Tract CancersRecruiting
Est. primary completion 2029-03 · NCT06564623 · CT.gov ↗
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Phase 3Advanced Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage IV Hepatocellular Carcinoma AJCC v8Recruiting
Est. primary completion 2029-03-10 · NCT07166406 · CT.gov ↗
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April 2029 (2)
Phase 2Gastroesophageal AdenocarcinomaNot yet recruiting
Est. primary completion 2029-04 · NCT07625930 · CT.gov ↗
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Phase 1/2Small Cell Lung CancerRecruiting
Est. primary completion 2029-04-27 · NCT06780137 · CT.gov ↗
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May 2029 (2)
Phase 3Non-Small Cell Lung CancerRecruiting
Est. primary completion 2029-05 · NCT06890598 · CT.gov ↗
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Phase 2Clinical Stage I Esophageal Adenocarcinoma AJCC v8, Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8 …Recruiting
Est. primary completion 2029-05-25 · NCT06078709 · CT.gov ↗
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June 2029 (1)
Phase 3Small Cell Lung CarcinomaActive not recruiting
Est. primary completion 2029-06-30 · NCT06992609 · CT.gov ↗
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July 2029 (4)
Phase 1/2Small-cell Lung Cancer, Neuroendocrine Carcinomas, Solid Tumor Show to Express DLL3Recruiting
Est. primary completion 2029-07 · NCT07174583 · CT.gov ↗
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Phase 2/3Gall Bladder CancerRecruiting
Est. primary completion 2029-07-21 · NCT06214572 · CT.gov ↗
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Phase 1/2Extensive Stage Lung Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8Recruiting
Est. primary completion 2029-07-25 · NCT06287775 · CT.gov ↗
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Phase 2Small Cell Lung Cancer Limited StageRecruiting
Est. primary completion 2029-07-31 · NCT07055581 · CT.gov ↗
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August 2029 (2)
Phase 2HCC, Tace, ImmunotherapyNot yet recruiting
Est. primary completion 2029-08-14 · NCT07168668 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerActive not recruiting
Est. primary completion 2029-08-31 · NCT03228667 · CT.gov ↗
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September 2029 (3)
Phase 1/2Biliary Tract Neoplasms, Advanced Cancer, ImmunotherapyNot yet recruiting
Est. primary completion 2029-09 · NCT07269158 · CT.gov ↗
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Phase 2/3Hepatocellular CarcinomaRecruiting
Est. primary completion 2029-09-14 · NCT06904170 · CT.gov ↗
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Phase 2Stage III Lung Cancer AJCC v8, Stage III Lung Non-Small Cell Cancer AJCC v7, Stage IIIA Lung Cancer AJCC v8 …Recruiting
Est. primary completion 2029-09-30 · NCT04892953 · CT.gov ↗
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October 2029 (3)
Phase 3Non-Small Cell Lung CancerRecruiting
Est. primary completion 2029-10 · NCT06284317 · CT.gov ↗
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Phase 1/2Lung Cancer, Liver Cancer, Colorectal Cancer, Pancreas Cancer, Ovary Cancer, Head and Neck Cancer, Breast Cancer, Gastric Cancer …Recruiting
Est. primary completion 2029-10-30 · NCT05187338 · CT.gov ↗
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Phase 2Small Cell Lung Cancer, SCLC, Extensive Stage Small Cell Lung Cancer, Limited Stage Small-Cell Lung CancerRecruiting
Est. primary completion 2029-10-31 · NCT05903092 · CT.gov ↗
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December 2029 (2)
Phase 2Bile Duct CancerRecruiting
Est. primary completion 2029-12-30 · NCT06274879 · CT.gov ↗
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Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2029-12-31 · NCT06810609 · CT.gov ↗
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2030 (17)
January 2030 (2)
Phase 2/3Endometrial CancerRecruiting
Est. primary completion 2030-01-01 · NCT05255653 · CT.gov ↗
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Phase 2Hepatocellular Carcinoma Non-resectableRecruiting
Est. primary completion 2030-01-02 · NCT07122089 · CT.gov ↗
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February 2030 (1)
Phase 2Esophagogastric AdenocarcinomaNot yet recruiting
Est. primary completion 2030-02-01 · NCT07507968 · CT.gov ↗
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April 2030 (3)
Phase 2Hepato Cellular CarcinomaRecruiting
Est. primary completion 2030-04-01 · NCT07489976 · CT.gov ↗
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Phase 1/2Folliculotropic Mycosis Fungoides, Recurrent Cutaneous T-Cell Non-Hodgkin Lymphoma, Recurrent Mycosis Fungoides …Recruiting
Est. primary completion 2030-04-14 · NCT03011814 · CT.gov ↗
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Phase 2CancerRecruiting
Est. primary completion 2030-04-30 · NCT03847649 · CT.gov ↗
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May 2030 (5)
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2030-05-28 · NCT05061550 · CT.gov ↗
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Phase 1Extensive Stage Small Cell Lung CancerActive not recruiting
Est. primary completion 2030-05-30 · NCT05361395 · CT.gov ↗
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Phase 1/2Stage III Hepatocellular Carcinoma AJCC v8, Stage III Intrahepatic Cholangiocarcinoma AJCC v8, Stage IV Hepatocellular Carcinoma AJCC v8 …Recruiting
Est. primary completion 2030-05-31 · NCT03942328 · CT.gov ↗
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Phase 2HCC - Hepatocellular Carcinoma, Tremelimumab, Durvalumab, RadiotherapyRecruiting
Est. primary completion 2030-05-31 · NCT06999707 · CT.gov ↗
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Phase 2HCC - Hepatocellular Carcinoma, Durvalumab, Tremelimumab, Proton RadiotherapyRecruiting
Est. primary completion 2030-05-31 · NCT06999694 · CT.gov ↗
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June 2030 (2)
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2030-06-25 · NCT07603856 · CT.gov ↗
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Phase 1Metastatic Biliary Tract Cancer, Metastatic Biliary Tract CarcinomaRecruiting
Est. primary completion 2030-06-30 · NCT07107750 · CT.gov ↗
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November 2030 (1)
Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2030-11 · NCT07759492 · CT.gov ↗
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December 2030 (3)
Phase 2Breast Neoplasms, Breast Cancer, Breast Tumors, Angiosarcoma, TNBC - Triple-Negative Breast Cancer, HER2-positive Breast Cancer …Recruiting
Est. primary completion 2030-12 · NCT01042379 · CT.gov ↗
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Phase 2Resectable Intrahepatic CholangiocarcinomaNot yet recruiting
Est. primary completion 2030-12-10 · NCT07639528 · CT.gov ↗
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Phase 2Liver Cancer, AntibodyRecruiting
Est. primary completion 2030-12-30 · NCT06482801 · CT.gov ↗
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2031 (4)
June 2031 (1)
Phase 1Small Cell Lung CancerActive not recruiting
Est. primary completion 2031-06-23 · NCT06898957 · CT.gov ↗
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October 2031 (1)
Phase 3Locally Advanced Lung Non-Small Cell Carcinoma, Stage IIB Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8Recruiting
Est. primary completion 2031-10-15 · NCT05624996 · CT.gov ↗
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November 2031 (1)
Phase 2MPNST, NF1, SarcomaRecruiting
Est. primary completion 2031-11-15 · NCT05253131 · CT.gov ↗
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December 2031 (1)
Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2031-12-30 · NCT07247786 · CT.gov ↗
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2032 (4)
May 2032 (1)
Phase 3Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma …Recruiting
Est. primary completion 2032-05-31 · NCT06058377 · CT.gov ↗
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July 2032 (1)
Phase 2Colorectal Cancer, Endometrial CancerRecruiting
Est. primary completion 2032-07-01 · NCT06680739 · CT.gov ↗
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August 2032 (1)
Phase 2Intrahepatic CholangiocarcinomaNot yet recruiting
Est. primary completion 2032-08 · NCT07766187 · CT.gov ↗
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December 2032 (1)
Phase 3Non-Small Cell Lung CancerRecruiting
Est. primary completion 2032-12-15 · NCT07554339 · CT.gov ↗
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2037 (1)
November 2037 (1)
Phase 3Limited Stage Small-Cell Lung CancerNot yet recruiting
Est. primary completion 2037-11 · NCT07637513 · CT.gov ↗
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2039 (1)
July 2039 (1)
Phase 3Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8Recruiting
Est. primary completion 2039-07-15 · NCT06498635 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (82)
Phase 2/3 (6)
Phase 2 (424)
Phase 1/2 (103)
Phase 1 (144)
Phase 4 (7)
Early phase / not applicable (11)
Used as active comparator (19)
Appears in other studies (4)