Asset profile

glasmacinal

Small molecule

Partialsignal

Evidence outlook · lead readout

NCT05572333 · Chronic Obstructive Pulmonary Disease, COPD

The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.

NCT05572333: The study randomized 61 participants to EP395 or matched placebo and kept participants and investigators blinded. Its primary outcomes were safety assessments rather than clinical improvement, and no primary-endpoint results are available, so the evidence remains limited.

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