Asset profile

Fulzerasib

Small molecule

Weaksignal

Evidence outlook · lead readout

NCT05756153 · Advance Non-small Cell Lung Cancer

The reported results come from study designs that frequently fail to replicate under controlled conditions — see the rationale below.

NCT05756153: The study was open-label, non-randomized, and had no comparator arm, with 47 participants. Its Phase II primary endpoint was objective response rate, a clinical tumor-response measure, but no primary-endpoint or safety results have been posted.

Interim analysis (ASCO 2024 late-breaking presentation, data cutoff before primary completion); single-arm response rate with no formal statistical threshold.

How the evidence outlook works ↗

Upcoming events

(4 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (3)
March 2027 (1)
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-03-31 · NCT07492342 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

April 2027 (1)
Phase 2KRAS G12C Lung CancerNot yet recruiting
Est. primary completion 2027-04-30 · NCT06936644 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

September 2027 (1)
Phase 2Lung Cancer (Non-Small Cell)Recruiting
Est. primary completion 2027-09 · NCT07198841 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2028 (1)
May 2028 (1)
Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2028-05-31 · NCT07463677 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

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