Asset profile
Esketamine · Spravato
Small molecule
Evidence outlook
Approved — Major Depressive Disorder
Regulatory approval supersedes design-level evidence grading — the trials behind approval are preserved below as the drug's evidence history.
track record: Reliable signal
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Featured trials
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Upcoming events
(4 total)
Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.
2028 (3)
June 2028 (2)
What to watch
Research analysis
Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.
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Research analysis
Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.
Sign in to access ResearchDecember 2028 (1)
What to watch
Research analysis
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April 2031 (1)
What to watch
Research analysis
Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.
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Competitive landscape
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