Asset profile

Mitizodone phosphate

Small molecule

Phase 3underway

Evidence outlook · registrational

Major Depressive Disorder: registrational readout pending

Entered Phase 3 on partial signal mid-stage evidence. Registrational readout expected around 2027-07.

NCT04591301: This single-ascending-dose study randomly assigned healthy volunteers to escalating doses of the drug or placebo under quadruple-blind conditions, a solid design for an early safety study, but its primary measure was the number of adverse events rather than a disease outcome, and results have not yet been reported.

How the evidence outlook works ↗

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
July 2027 (1)
Phase 2/3Major Depressive DisorderRecruiting
Est. primary completion 2027-07 · NCT04984512 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

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