Asset profile

CPL207280

Small molecule

Phase 2GPR40 / FFAR1No recent registered activity
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Partialdesign only

Evidence outlook · results not reported

NCT05248776 · Type 2 Diabetes

The lead study's design has limits that temper confidence (see the rationale below), and its results have not been reported. This tier describes the design, not an outcome.

NCT05248776: This is a randomized, double-blind, placebo-controlled trial, which is a strong design, but its primary measured outcome is a short-term glucose-tolerance-test response rather than HbA1c, the standard longer-term measure of blood sugar control for diabetes drugs. Results have not yet been posted.

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 60 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
CPL207280: this drugPhase 2Small moleculeGPR40 / FFAR1
AfrezzaApprovedPeptideInsulin receptor (basal), Insulin
Alogliptin (Nesina)ApprovedSmall moleculeDPP-4
Bexagliflozin (Brenzavvy)ApprovedSmall moleculeSGLT2
Canagliflozin (Invokana)ApprovedSmall moleculeSGLT2
Dapagliflozin (Farxiga / Forxiga)ApprovedSmall moleculeSGLT2
Dulaglutide (Trulicity)ApprovedPeptideGLP-1 receptor
Empagliflozin (Jardiance)ApprovedSmall moleculeSGLT2
Ertugliflozin (Steglatro)ApprovedSmall moleculeSGLT2
Glipizide (Glucotrol)ApprovedSmall moleculeSulfonylurea receptor (SUR1)
Glyburide (Diabeta / Micronase)ApprovedSmall moleculeSulfonylurea receptor (SUR1)
Insulin Aspart (NovoLog / Fiasp)ApprovedPeptideInsulin receptor
Insulin Degludec (Tresiba)ApprovedPeptideInsulin receptor (basal)
Insulin Detemir (Levemir)ApprovedPeptideInsulin receptor (basal)
Insulin Glargine (Lantus / Toujeo)ApprovedPeptideInsulin receptor (basal)
Insulin Glulisine (Apidra)ApprovedPeptideInsulin receptor (basal)

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (1)
Phase 1 (1)