Asset profile

SCTB41

Multispecific antibody

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Phase 3underway

Evidence outlook · registrational

Non-Small Cell Lung Cancer: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2030-01-24.

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 60 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
SCTB41: this drugPhase 2/3Multispecific antibodyPD-1 / VEGF / TGF-β receptor II (TGFβRII)
Afatinib (Gilotrif)ApprovedSmall moleculeEGFR/HER1, HER2, HER4
Alectinib (Alecensa)ApprovedSmall moleculeALK
Alymsys (bevacizumab-Maly)ApprovedMonoclonal antibodyVEGF-A
AmivantamabApprovedMultispecific antibodyEGFR x c-MET
AtezolizumabApprovedMonoclonal antibodyPD-L1
BAT1706 (Avzivi)ApprovedMonoclonal antibodyVEGF-A
BAY2927088 (Hyrnuo)ApprovedSmall moleculeHER2 (ERBB2) exon 20 insertions and point mutations; also mutant-selective EGFR
BevacizumabApprovedMonoclonal antibodyVEGF-A, Vascular Endothelial Growth Factor Inhibitor
Bevacizumab-Awwb (MVASI)ApprovedMonoclonal antibodyVEGF-A
BinimetinibApprovedSmall moleculeMEK1/2
BrigatinibApprovedSmall moleculeALK
CapmatinibApprovedSmall moleculeMET
CemiplimabApprovedMonoclonal antibodyPD-1
CeritinibApprovedSmall moleculeALK
CrizotinibApprovedSmall moleculeALK, ROS1, MET/HGFR, and RON

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(5 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
April 2027 (1)
Phase 1/2Advanced Malignant Solid TumoursRecruiting
Est. primary completion 2027-04-30 · NCT06600022 · CT.gov ↗
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2028 (1)
October 2028 (1)
Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2028-10 · NCT07609251 · CT.gov ↗
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2029 (2)
May 2029 (1)
Phase 1/2Advanced Malignant Solid TumorNot yet recruiting
Est. primary completion 2029-05-30 · NCT07594028 · CT.gov ↗
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June 2029 (1)
Phase 1/2Advanced Malignant Solid TumorsNot yet recruiting
Est. primary completion 2029-06-30 · NCT07665970 · CT.gov ↗
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2030 (1)
January 2030 (1)
Phase 2/3Double BlindRecruiting
Est. primary completion 2030-01-24 · NCT07662395 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2/3 (1)
Phase 2 (1)
Phase 1/2 (3)