Asset profile

KSP-0243

Small molecule

Phase 2Undisclosed / early pipeline
Partialsignal

Evidence outlook · lead readout

NCT05831670 · Colitis, Ulcerative

The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.

NCT05831670: The trial randomized 108 participants to KSP-0243 or placebo with participants, clinicians, investigators, and outcome assessors masked. Its primary endpoint was clinical response based on the modified Mayo score at Week 8, but the registry does not report whether the comparison was met.

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