Asset profile
INCB161734
Small molecule
Evidence outlook · registrational
Non-Small Cell Lung Cancer: registrational readout pending
Its supporting mid-stage evidence has not yet been graded on this platform. No registrational readout date is posted for this indication; a Phase 3 is registered in Solid Tumors (NCT07522073); see the registry list.
How the evidence outlook works ↗
Featured trials
The studies most instrumental to this drug's clinical progression, individually graded on design and result. Pick an indication; Research unlocks the trials, endpoints, key results and grades.
Competitive landscape
71 competitors in this universe: 11 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 58 further along in development.
| Drug | Stage | Modality | Mechanism | Evidence signal | Reported efficacygraded featured trials |
|---|---|---|---|---|---|
| INCB161734: this drug | Phase 3 | Small molecule | KRAS G12D | ||
| GFH375 | Phase 3 | Small molecule | KRAS G12D | ||
| Setidegrasib | Phase 3 | Small molecule | KRAS G12D | ||
| Zoldonrasib | Phase 3 | Small molecule | KRAS G12D | ||
| VS-7375 | Phase 2 | Small molecule | KRAS G12D | ||
| ARV-806 | Phase 1/2 | Small molecule | KRAS G12D | ||
| INV-8989 | Phase 1/2 | Small molecule | KRAS G12D | ||
| QLC1101 | Phase 1/2 | Small molecule | KRAS G12D | ||
| RMC-9805 | Phase 1/2 | Small molecule | KRAS G12D | ||
| TSN1611 | Phase 1/2 | Small molecule | KRAS G12D | ||
| LT-010391 | Phase 1 | Small molecule | KRAS G12D | ||
| LY3962673 | Phase 1 | Small molecule | KRAS G12D | ||
| Afatinib (Gilotrif) | Approved | Small molecule | EGFR/HER1, HER2, HER4 | ||
| Alectinib (Alecensa) | Approved | Small molecule | ALK | ||
| Alymsys (bevacizumab-Maly) | Approved | Monoclonal antibody | VEGF-A | ||
| Amivantamab | Approved | Multispecific antibody | EGFR x c-MET |
…and 56 more. Research shows the complete landscape.
Unlock the full comparison
Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.
Upcoming events
(2 total)
Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.
All registered studies
Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.