Asset profile

GC101

Cell therapy

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 58 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
GC101: this drugPhase 3Cell therapyAutologous tumor neoantigens (polyclonal, patient-specific)
Afatinib (Gilotrif)ApprovedSmall moleculeEGFR/HER1, HER2, HER4
Alectinib (Alecensa)ApprovedSmall moleculeALK
Alymsys (bevacizumab-Maly)ApprovedMonoclonal antibodyVEGF-A
AmivantamabApprovedMultispecific antibodyEGFR x c-MET
AtezolizumabApprovedMonoclonal antibodyPD-L1
BAT1706 (Avzivi)ApprovedMonoclonal antibodyVEGF-A
BAY2927088 (Hyrnuo)ApprovedSmall moleculeHER2 (ERBB2) exon 20 insertions and point mutations; also mutant-selective EGFR
BevacizumabApprovedMonoclonal antibodyVEGF-A, Vascular Endothelial Growth Factor Inhibitor
Bevacizumab-Awwb (MVASI)ApprovedMonoclonal antibodyVEGF-A
BinimetinibApprovedSmall moleculeMEK1/2
BrigatinibApprovedSmall moleculeALK
CapmatinibApprovedSmall moleculeMET
CemiplimabApprovedMonoclonal antibodyPD-1
CeritinibApprovedSmall moleculeALK
CrizotinibApprovedSmall moleculeALK, ROS1, MET/HGFR, and RON

…and 45 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(10 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (5)
December 2026 (5)
Phase 1/2Spinal Muscular Atrophy Type 3Recruiting
Est. primary completion 2026-12 · NCT06421831 · CT.gov ↗
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Phase 1/2Spinal Muscular AtrophyRecruiting
Est. primary completion 2026-12 · NCT05824169 · CT.gov ↗
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Phase 1Breast Cancer, Treatment Side Effects, Advanced Breast Cancer, Effects of ImmunotherapyRecruiting
Est. primary completion 2026-12-20 · NCT05142475 · CT.gov ↗
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Phase 1GliomaRecruiting
Est. primary completion 2026-12-30 · NCT04943913 · CT.gov ↗
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Phase 3SMA - Spinal Muscular AtrophyRecruiting
Est. primary completion 2026-12-31 · NCT06971094 · CT.gov ↗
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2027 (5)
January 2027 (1)
Phase 1Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-01-01 · NCT06473961 · CT.gov ↗
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June 2027 (1)
Phase 2Non-Small Cell Lung CancerRecruiting
Est. primary completion 2027-06-01 · NCT07560111 · CT.gov ↗
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September 2027 (1)
Phase 1Solid Tumor, AdultNot yet recruiting
Est. primary completion 2027-09-20 · NCT07294872 · CT.gov ↗
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December 2027 (2)
Phase 1Advanced Solid TumorsRecruiting
Est. primary completion 2027-12-22 · NCT04967833 · CT.gov ↗
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Phase 1Gastrointestinal TumorRecruiting
Est. primary completion 2027-12-30 · NCT04960072 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Phase 2 (2)
Phase 1/2 (4)
Phase 1 (9)
Appears in other studies (1)