Asset profile

BPI-371153

Small molecule

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Earlyevidence

Evidence outlook

Early-stage evidence only

Phase 1 / first-in-human studies establish safety, tolerability, and dosing; they are not designed to demonstrate efficacy, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

71 competitors in this universe: 10 direct rivals (same mechanism and indication), 1 same-class, 60 same-indication; 69 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
BPI-371153: this drugPhase 1Small moleculePD-L1
AtezolizumabApprovedMonoclonal antibodyPD-L1
DurvalumabApprovedMonoclonal antibodyPD-L1
Tecentriq Hybreza (atezolizumab And Hyaluronidase-Tqjs)ApprovedMonoclonal antibodyPD-L1
AdebrelimabPhase 3Monoclonal antibodyPD-L1
CS1001 Monoclonal AntibodyPhase 3Monoclonal antibodyPD-L1
EnvafolimabPhase 3Monoclonal antibodyPD-L1
KL-A167Phase 3Monoclonal antibodyPD-L1
PF-08046054Phase 3Antibody–drug conjugatePD-L1
HLX43Phase 2/3Antibody–drug conjugatePD-L1
177Lu-RAD204Phase 1RadiopharmaceuticalPD-L1
IBC-Ab002Phase 1Monoclonal antibodyPD-L1
Afatinib (Gilotrif)ApprovedSmall moleculeEGFR/HER1, HER2, HER4
Alectinib (Alecensa)ApprovedSmall moleculeALK
Alymsys (bevacizumab-Maly)ApprovedMonoclonal antibodyVEGF-A
AmivantamabApprovedMultispecific antibodyEGFR x c-MET

…and 56 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 1Non-Small Cell Lung CancerRecruiting
Est. primary completion 2026-12 · NCT05341557 · CT.gov ↗
What to watch
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All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.