Asset profile
VH4524184
Small molecule
Evidence outlook · lead readout
NCT06214052 · HIV Infections
The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.
NCT06214052: The study was randomized and double-blind with matching placebo, but it was very small, with 6, 6, and 7 participants receiving VH4524184 doses and only 3 receiving placebo. Its primary endpoint was a surrogate measure of plasma HIV-1 RNA change, and although the reported mean changes favored the medium and high doses, statistical significance was not reported.
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Upcoming events
(1 total)
Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.
2027 (1)
June 2027 (1)
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