Asset profile

AGT103-T

Gene therapy / editing

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Earlyevidence

Evidence outlook

Early-stage evidence only

Phase 1 / first-in-human studies establish safety, tolerability, and dosing; they are not designed to demonstrate efficacy, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 49 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
AGT103-T: this drugPhase 1Gene therapy / editingHIV proviral reservoir / autologous T cells
Bictegravir (Biktarvy)ApprovedSmall moleculeHIV integrase
Cabotegravir (Vocabria / Cabenuva / Apretude)ApprovedSmall moleculeHIV integrase
Crofelemer (Mytesi)ApprovedSmall moleculeChloride channel (intestinal epithelium)
Darunavir (Prezista)ApprovedSmall moleculeHIV protease
Dolutegravir (Tivicay / Triumeq / Dovato / Juluca (component))ApprovedSmall moleculeHIV integrase
Doravirine (Pifeltro)ApprovedSmall moleculeHIV reverse transcriptase
Elsulfavirine (Elpida)ApprovedSmall moleculeHIV reverse transcriptase
Elvitegravir (Stribild / Genvoya (component))ApprovedSmall moleculeHIV integrase
Emtricitabine / Tenofovir Disoproxil Fumarate (Truvada)ApprovedSmall moleculeHIV reverse transcriptase
Etravirine (Intelence)ApprovedSmall moleculeHIV reverse transcriptase
Fosamprenavir (Lexiva / Telzir)ApprovedSmall moleculeHIV protease
Fostemsavir (Rukobia)ApprovedSmall moleculeHIV gp120
Ibalizumab (Trogarzo)ApprovedMonoclonal antibodyCD4 receptor
Lenacapavir (Sunlenca / Yeztugo)ApprovedSmall moleculeHIV capsid
Maraviroc (Selzentry / Celsentri)ApprovedSmall moleculeCCR5 co-receptor

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.