Asset profile
Dapivirine · Dapivirine Vaginal Ring
Small molecule
Evidence outlook
Approved: HIV-1 prevention in women (dapivirine vaginal ring; EMA Art. 58 opinion + WHO... (ZW)
This approval is outside the US-scoped market view; the covered program shown here is investigational. Regulatory approval supersedes design-level evidence grading for the approved use.
track record: Partial signal
How the evidence outlook works ↗
Featured trials
The studies most instrumental to this drug's clinical progression, individually graded on design and result. Pick an indication; Research unlocks the trials, endpoints, key results and grades.
Competitive landscape
60 competitors in this universe: 11 direct rivals (same mechanism and indication), 0 same-class, 49 same-indication; 21 further along in development.
| Drug | Stage | Modality | Mechanism | Evidence signal | Reported efficacygraded featured trials |
|---|---|---|---|---|---|
| Dapivirine (Dapivirine Vaginal Ring): this drug | Phase 3 | Small molecule | HIV reverse transcriptase | ||
| Doravirine (Pifeltro) | Approved | Small molecule | HIV reverse transcriptase | ||
| Elsulfavirine (Elpida) | Approved | Small molecule | HIV reverse transcriptase | ||
| Emtricitabine / Tenofovir Disoproxil Fumarate (Truvada) | Approved | Small molecule | HIV reverse transcriptase | ||
| Etravirine (Intelence) | Approved | Small molecule | HIV reverse transcriptase | ||
| Rilpivirine (Edurant) | Approved | Small molecule | HIV reverse transcriptase | ||
| Tenofovir Alafenamide / Emtricitabine (Descovy) | Approved | Small molecule | HIV reverse transcriptase | ||
| Alimatravir | Phase 3 | Small molecule | HIV reverse transcriptase | ||
| Azvudine (FNC) | Phase 3 | Small molecule | HIV reverse transcriptase | ||
| Ulonivirine | Phase 2/3 | Small molecule | HIV reverse transcriptase | ||
| CL-197 | Phase 2 | Small molecule | HIV reverse transcriptase | ||
| Ainuovirine | Phase 1 | Small molecule | HIV reverse transcriptase | ||
| Bictegravir (Biktarvy) | Approved | Small molecule | HIV integrase | ||
| Cabotegravir (Vocabria / Cabenuva / Apretude) | Approved | Small molecule | HIV integrase | ||
| Crofelemer (Mytesi) | Approved | Small molecule | Chloride channel (intestinal epithelium) | ||
| Darunavir (Prezista) | Approved | Small molecule | HIV protease |
…and 45 more. Research shows the complete landscape.
Unlock the full comparison
Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.
Compare head-to-head
5 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.
Upcoming events
No upcoming readouts on record for this asset.
All registered studies
Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.