Asset profile

Fosamprenavir · Lexiva / Telzir

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: HIV

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Partial signal

How the evidence outlook works ↗

Competitive landscape

60 competitors in this universe: 2 direct rivals (same mechanism and indication), 0 same-class, 58 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Fosamprenavir (Lexiva / Telzir): this drugApprovedSmall moleculeHIV protease
Darunavir (Prezista)ApprovedSmall moleculeHIV protease
Tipranavir (Aptivus)ApprovedSmall moleculeHIV protease
Bictegravir (Biktarvy)ApprovedSmall moleculeHIV integrase
Cabotegravir (Vocabria / Cabenuva / Apretude)ApprovedSmall moleculeHIV integrase
Crofelemer (Mytesi)ApprovedSmall moleculeChloride channel (intestinal epithelium)
Dolutegravir (Tivicay / Triumeq / Dovato / Juluca (component))ApprovedSmall moleculeHIV integrase
Doravirine (Pifeltro)ApprovedSmall moleculeHIV reverse transcriptase
Elsulfavirine (Elpida)ApprovedSmall moleculeHIV reverse transcriptase
Elvitegravir (Stribild / Genvoya (component))ApprovedSmall moleculeHIV integrase
Emtricitabine / Tenofovir Disoproxil Fumarate (Truvada)ApprovedSmall moleculeHIV reverse transcriptase
Etravirine (Intelence)ApprovedSmall moleculeHIV reverse transcriptase
Fostemsavir (Rukobia)ApprovedSmall moleculeHIV gp120
Ibalizumab (Trogarzo)ApprovedMonoclonal antibodyCD4 receptor
Lenacapavir (Sunlenca / Yeztugo)ApprovedSmall moleculeHIV capsid
Maraviroc (Selzentry / Celsentri)ApprovedSmall moleculeCCR5 co-receptor

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
July 2027 (1)
Phase 2Laryngopharyngeal RefluxRecruiting
Est. primary completion 2027-07-01 · NCT04383262 · CT.gov ↗
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2028 (1)
December 2028 (1)
Phase 2Refractory Gastroesophageal Reflux Disease, Gastroesophageal Reflux DiseaseNot yet recruiting
Est. primary completion 2028-12-31 · NCT06704100 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (12)
Phase 2 (8)
Phase 1 (8)
Phase 4 (4)
Early phase / not applicable (3)
Studied as part of a combination product (1)
Appears in other studies (12)