Asset profile

Semzuvolimab

Monoclonal antibody

Phase 3underway

Evidence outlook · registrational

HIV: registrational readout pending

Entered Phase 3 on partial signal mid-stage evidence. No upcoming registrational readout date is posted to the registry — check News for topline announcements.

NCT03743376: The study randomized 31 participants to two semzuvolimab dosing schedules or standard antiretroviral therapy, but it was open-label rather than blinded. Its primary safety endpoint was a clinical adverse-event measure, although the comparison cannot be judged because results are not posted.

How the evidence outlook works ↗

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 2HIVNot yet recruiting
Est. primary completion 2026-12 · NCT04985890 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

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