Asset profile

UBT251

Peptide

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Phase 3underway

Evidence outlook · registrational

Obesity: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2027-09-29.

Also in development:Chronic Kidney Disease · Phase 2

How the evidence outlook works ↗

Competitive landscape

123 competitors in this universe: 5 direct rivals (same mechanism and indication), 0 same-class, 118 same-indication; 32 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
UBT251: this drugPhase 3PeptideGLP-1/GIP/glucagon receptor (triple)
RetatrutidePhase 3PeptideGLP-1/GIP/glucagon receptor (triple)
HM15211Phase 2PeptideGLP-1/GIP/glucagon receptor (triple)
HM15275Phase 2PeptideGLP-1/GIP/glucagon receptor (triple)
HRS-4729Phase 2PeptideGLP-1/GIP/glucagon receptor (triple)
NNC0662-0419Phase 2PeptideGLP-1/GIP/glucagon receptor (triple)
Atrasentan (Vanrafia)ApprovedSmall moleculeEndothelin A receptor
Avacopan (Tavneos)ApprovedSmall moleculeComplement C5a receptor 1 (C5aR1/CD88)
Baxdrostat (Baxfendy)ApprovedSmall moleculeAldosterone synthase (CYP11B2)
Budesonide (targeted-Release) (TARPEYO / Nefecon)ApprovedSmall moleculeGlucocorticoid receptor
Canagliflozin (Invokana)ApprovedSmall moleculeSGLT2
Dapagliflozin (Farxiga / Forxiga)ApprovedSmall moleculeSGLT2
Daprodustat (Jesduvroq)ApprovedSmall moleculeHIF prolyl hydroxylase (HIF-PH1/2/3)
Difelikefalin (Korsuva)ApprovedPeptideKappa-opioid receptor (agonist, peripherally restricted)
Empagliflozin (Jardiance)ApprovedSmall moleculeSGLT2
Etelcalcetide (Parsabiv)ApprovedPeptideCalcium-sensing receptor (CaSR), allosteric agonist on parathyroid chief cells

…and 108 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(12 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 1Drug Drug Interaction (DDI); Pharmacokinetics and PharmacodynamicsRecruiting
Est. primary completion 2026-12 · NCT07785934 · CT.gov ↗
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2027 (7)
January 2027 (1)
Phase 2ObesityRecruiting
Est. primary completion 2027-01-14 · NCT07395687 · CT.gov ↗
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April 2027 (2)
Phase 1ObesityRecruiting
Est. primary completion 2027-04-07 · NCT07710768 · CT.gov ↗
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Phase 1ObesityRecruiting
Est. primary completion 2027-04-27 · NCT07710729 · CT.gov ↗
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June 2027 (1)
Phase 2Metabolic Dysfunction-associated Steatohepatitis (MASH)Recruiting
Est. primary completion 2027-06-04 · NCT07145151 · CT.gov ↗
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September 2027 (2)
Phase 3Type 2 DiabetesNot yet recruiting
Est. primary completion 2027-09-24 · NCT07659574 · CT.gov ↗
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Phase 3ObesityNot yet recruiting
Est. primary completion 2027-09-29 · NCT07648225 · CT.gov ↗
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October 2027 (1)
Phase 2Diabetes Mellitus, Type 2Recruiting
Est. primary completion 2027-10-04 · NCT07668388 · CT.gov ↗
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2028 (2)
February 2028 (1)
Phase 3Type 2 DiabetesNot yet recruiting
Est. primary completion 2028-02-29 · NCT07653477 · CT.gov ↗
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September 2028 (1)
Phase 3ObesityNot yet recruiting
Est. primary completion 2028-09 · NCT07767942 · CT.gov ↗
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2029 (1)
March 2029 (1)
Phase 3ObesityNot yet recruiting
Est. primary completion 2029-03 · NCT07806851 · CT.gov ↗
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2030 (1)
July 2030 (1)
Phase 2Chronic Kidney DiseaseRecruiting
Est. primary completion 2030-07-11 · NCT07134335 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (5)
Phase 2 (5)
Phase 1 (3)
Appears in other studies (1)