Asset profile

Sodium zirconium cyclosilicate · Lokelma

Small molecule

Approvedregulatory verdict

Evidence outlook

Approved — Heart Failure

Regulatory approval supersedes design-level evidence grading — the trials behind approval are preserved below as the drug's evidence history.

track record: Partial signal

Also in development:Chronic Kidney Disease · Phase 3

How the evidence outlook works ↗

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 3Chronic Kidney DiseaseRecruiting
Est. primary completion 2026-12-30 · NCT06578078 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

All registered studies

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