Asset profile

Desidustat · Oxemia

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: Anaemia associated with chronic kidney disease (Oxemia) (IN)

This approval is outside the US-scoped market view; the covered program shown here is investigational. Regulatory approval supersedes design-level evidence grading for the approved use.

track record: Partial signal

Source for the program status

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Competitive landscape

67 competitors in this universe: 7 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 25 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Desidustat (Oxemia): this drugPhase 3Small moleculeHIF prolyl hydroxylase (HIF-PH1/2/3)
Daprodustat (Jesduvroq)ApprovedSmall moleculeHIF prolyl hydroxylase (HIF-PH1/2/3)
Vadadustat (Vafseo)ApprovedSmall moleculeHIF prolyl hydroxylase (HIF-PH1/2/3)
AND017Phase 3Small moleculeHIF prolyl hydroxylase (HIF-PH1/2/3)
EnarodustatPhase 3Small moleculeHIF prolyl hydroxylase (HIF-PH1/2/3)
MolidustatPhase 3Small moleculeHIF prolyl hydroxylase (HIF-PH1/2/3)
Roxadustat (Evrenzo)Phase 3Small moleculeHIF prolyl hydroxylase (HIF-PH1/2/3)
SSS17Phase 2Small moleculeHIF prolyl hydroxylase (HIF-PH1/2/3)
Atrasentan (Vanrafia)ApprovedSmall moleculeEndothelin A receptor
Avacopan (Tavneos)ApprovedSmall moleculeComplement C5a receptor 1 (C5aR1/CD88)
Baxdrostat (Baxfendy)ApprovedSmall moleculeAldosterone synthase (CYP11B2)
Budesonide (targeted-Release) (TARPEYO / Nefecon)ApprovedSmall moleculeGlucocorticoid receptor
Canagliflozin (Invokana)ApprovedSmall moleculeSGLT2
Dapagliflozin (Farxiga / Forxiga)ApprovedSmall moleculeSGLT2
Difelikefalin (Korsuva)ApprovedPeptideKappa-opioid receptor (agonist, peripherally restricted)
Empagliflozin (Jardiance)ApprovedSmall moleculeSGLT2

…and 52 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (2)
Phase 2 (1)
Phase 1 (1)
Phase 4 (1)