Asset profile

HM15275

Peptide

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

How the evidence outlook works ↗

Competitive landscape

65 competitors in this universe: 5 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 51 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
HM15275: this drugPhase 2PeptideGLP-1/GIP/glucagon receptor (triple)
RetatrutidePhase 3PeptideGLP-1/GIP/glucagon receptor (triple)
UBT251Phase 3PeptideGLP-1/GIP/glucagon receptor (triple)
HM15211Phase 2PeptideGLP-1/GIP/glucagon receptor (triple)
HRS-4729Phase 2PeptideGLP-1/GIP/glucagon receptor (triple)
NNC0662-0419Phase 2PeptideGLP-1/GIP/glucagon receptor (triple)
Liraglutide (Saxenda / Victoza)ApprovedPeptideGLP-1 receptor
Naltrexone / Bupropion (Contrave)ApprovedSmall moleculeOpioid receptor / dopamine (combination)
Orforglipron (Foundayo)ApprovedSmall moleculeGLP-1 receptor
Orlistat (Xenical / Alli)ApprovedSmall moleculePancreatic/gastric lipase
Phentermine / Topiramate (Qsymia)ApprovedSmall moleculeNoradrenergic/anticonvulsant (combination)
Semaglutide (Wegovy / Ozempic / Rybelsus)ApprovedPeptideGLP-1 receptor
Setmelanotide (Imcivree)ApprovedPeptideMC4R
Tirzepatide (Zepbound / Mounjaro)ApprovedPeptideGLP-1/GIP receptor (dual)
AleniglipronPhase 3Small moleculeGLP-1 receptor
AmycretinPhase 3PeptideGLP-1 receptor, Amylin receptor

…and 50 more. Research shows the complete landscape.

Research

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (2)
January 2027 (1)
Phase 2ObesityActive not recruiting
Est. primary completion 2027-01 · NCT07205900 · CT.gov ↗
What to watch
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October 2027 (1)
Phase 2Type 2 Diabetes Mellitus, T2DMRecruiting
Est. primary completion 2027-10 · NCT07527650 · CT.gov ↗
What to watch
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (2)
Phase 1 (1)