Asset profile

SHR-1139

Monoclonal antibody

Partialsignal

Evidence outlook · lead readout

NCT07051538 · Moderate to Severe Plaque Psoriasis

The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.

NCT07051538: This early-phase study randomized 64 participants to SHR-1139 or placebo under full blinding, but it was designed to check safety and tolerability, not to test whether the drug improves psoriasis, and no results have been posted, so no conclusion about benefit can yet be drawn from it.

Also in development:Ulcerative Colitis · Phase 2

How the evidence outlook works ↗

Upcoming events

(3 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 2PsoriasisRecruiting
Est. primary completion 2026-12-31 · NCT07719530 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2027 (2)
July 2027 (1)
Phase 2PsoriasisNot yet recruiting
Est. primary completion 2027-07 · NCT07758075 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

August 2027 (1)
Phase 2Ulcerative ColitisActive not recruiting
Est. primary completion 2027-08 · NCT07232576 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

All registered studies

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Competitive landscape

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