Asset profile

QiShenYiQi

Botanical

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Partialdesign only

Evidence outlook · results not reported

NCT04944706 · Chronic Heart Failure With Preserved Ejection Fraction

The lead study's design has limits that temper confidence (see the rationale below), and its results have not been reported. This tier describes the design, not an outcome.

NCT04944706: The study was randomized and quadruple-blinded, with two QiShenYiQi dose groups and a placebo group, and enrolled 225 participants. Its primary clinical functional endpoint was 6-minute walking distance, but whether that endpoint was met cannot be determined because results are not posted.

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Competitive landscape

65 competitors in this universe: 2 direct rivals (same mechanism and indication), 3 same-class, 60 same-indication; 42 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
QiShenYiQi: this drugPhase 2BotanicalMulti-target (ginsenoside)
Shenfu Injection (Shenfu Zhusheye)Phase 2/3BotanicalMulti-target (ginsenoside)
Jia Shen TabletPhase 2BotanicalMulti-target (ginsenoside)
CerebrolysinPhase 3PeptideMulti-target (ginsenoside)
MLC901 (NeuroAiD II)Phase 3BotanicalMulti-target (ginsenoside)
PM012Phase 2/3BotanicalMulti-target (ginsenoside)
Baxdrostat (Baxfendy)ApprovedSmall moleculeAldosterone synthase (CYP11B2)
Dapagliflozin (Farxiga / Forxiga)ApprovedSmall moleculeSGLT2
Empagliflozin (Jardiance)ApprovedSmall moleculeSGLT2
Ferric Carboxymaltose (Injectafer / Ferinject)ApprovedIron Complex (iv)Iron repletion
Ferric Derisomaltose (Monoferric / Monofer)ApprovedIron Complex (iv)Iron repletion
Finerenone (Kerendia)ApprovedSmall moleculeMineralocorticoid receptor
Furosemide (subcutaneous, scPharmaceuticals) (FUROSCIX)ApprovedSmall moleculeNKCC2
Furosemide (subcutaneous, SQ Innovation) (Lasix ONYU)ApprovedSmall moleculeNKCC2
Icodextrin (peritoneal Ultrafiltration) (Extraneal)ApprovedDevice Solution (peritoneal Dialysis)Peritoneal ultrafiltration
Isosorbide Dinitrate / Hydralazine (BiDil)ApprovedSmall moleculeHydralazine/isosorbide dinitrate (fixed combination)

…and 50 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 4Heart FailureNot yet recruiting
Est. primary completion 2026-12-31 · NCT06699407 · CT.gov ↗
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All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (1)
Phase 1 (1)
Phase 4 (3)
Appears in other studies (3)