Asset profile

LM11A-31

Small molecule

Phase 2p75 neurotrophin receptorNo recent registered activity
Partialsignal

Evidence outlook · lead readout

NCT03069014 · Mild to Moderate Alzheimer's Disease

The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.

NCT03069014: The study randomized 242 participants to two LM11A-31-BHS doses or placebo and masked participants, care providers, and investigators. Its primary endpoint concerned adverse events and other safety measures, but no results were posted, so whether the primary comparison was favorable or statistically significant cannot be determined.

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