Asset profile

Enrupatinib

Small molecule

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

61 competitors in this universe: 0 direct rivals (same mechanism and indication), 1 same-class, 60 same-indication; 32 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Enrupatinib: this drugPhase 2Small moleculeCSF-1R
AxatilimabApprovedMonoclonal antibodyCSF-1R
Benzgalantamine (Zunveyl)ApprovedSmall moleculeAcetylcholinesterase/nicotinic receptor (prodrug)
Brexpiprazole (Rexulti)ApprovedSmall moleculeDopamine D2/D3 and serotonin 5-HT1A receptor
Dextromethorphan / Bupropion (Auvelity)ApprovedSmall moleculesigma-1/NMDA
Donanemab (Kisunla)ApprovedMonoclonal antibodyAmyloid-beta (monoclonal antibody)
Lecanemab (Leqembi)ApprovedMonoclonal antibodyAmyloid-beta (monoclonal antibody)
Xanomeline / Trospium Chloride (Cobenfy)ApprovedSmall moleculeMuscarinic M1/M4 receptor (agonist/antagonist combination)
ACP-204Phase 3Small moleculeSerotonin 5-HT2A receptor (antagonist / inverse agonist)
AR1001Phase 3Small moleculePDE5
BezisterimPhase 3Small moleculeERK/NF-kB inflammatory
BlarcamesinePhase 3Small moleculeSigma-1 receptor / muscarinic receptor (dual)
BuntanetapPhase 3Small moleculeAPP/tau/alpha-synuclein/TDP-43 (translation)
CerebrolysinPhase 3PeptideMulti-target (ginsenoside)
GV1001Phase 3PeptideTelomerase (hTERT)
Hydromethylthionine MesylatePhase 3Small moleculeTau aggregation; Acetylcholine

…and 46 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 2Alzheimer's DiseaseRecruiting
Est. primary completion 2026-12 · NCT06745583 · CT.gov ↗
What to watch
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All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (1)
Appears in other studies (1)