Asset profile

Lecanemab · Leqembi

Monoclonal antibody

Approvedregulatory verdict

Evidence outlook

Approved — Alzheimer's Disease

Regulatory approval supersedes design-level evidence grading — the trials behind approval are preserved below as the drug's evidence history.

track record: Partial signal

How the evidence outlook works ↗

Upcoming events

(7 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 2Alzheimer's DiseaseActive not recruiting
Est. primary completion 2026-12-03 · NCT06602258 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2028 (4)
April 2028 (3)
Phase 2/3Alzheimer's DiseaseActive not recruiting
Est. primary completion 2028-04 · NCT01760005 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 2/3Alzheimer's DiseaseActive not recruiting
Est. primary completion 2028-04 · NCT05269394 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 2Alzheimer's DiseaseNot yet recruiting
Est. primary completion 2028-04-01 · NCT07212062 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

December 2028 (1)
Phase 3Alzheimer's DiseaseActive not recruiting
Est. primary completion 2028-12-21 · NCT04468659 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2029 (1)
June 2029 (1)
Phase 3Alzheimer's DiseaseActive not recruiting
Est. primary completion 2029-06-30 · NCT03887455 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2030 (1)
June 2030 (1)
Phase 3Alzheimer's DiseaseActive not recruiting
Est. primary completion 2030-06 · NCT06384573 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

All registered studies

Research

Unlock the complete ClinicalTrials.gov registry

Research includes every linked study, indication filters, phase grouping and featured-trial cross-links.

Competitive landscape

Research

Unlock the competitor landscape

Research compares assets by shared mechanism and indication, including each competitor's stage in the relevant market.