Asset profile

Donanemab · Kisunla

Monoclonal antibody

Approvedregulatory verdict

Evidence outlook

Approved — Alzheimer's Disease

Regulatory approval supersedes design-level evidence grading — the trials behind approval are preserved below as the drug's evidence history.

track record: Partial signal

How the evidence outlook works ↗

Upcoming events

(7 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
November 2027 (1)
Phase 3Alzheimer's DiseaseActive not recruiting
Est. primary completion 2027-11 · NCT05026866 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2028 (3)
May 2028 (1)
Phase 3Alzheimer's DiseaseActive not recruiting
Est. primary completion 2028-05 · NCT05508789 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

August 2028 (2)
Phase 2Cognitive Dysfunction, Lewy Body Disease, Synucleinopathies, AmyloidRecruiting
Est. primary completion 2028-08 · NCT07589595 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

Phase 2Alzheimer's DiseaseEnrolling by invitation
Est. primary completion 2028-08-31 · NCT07167966 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2029 (1)
September 2029 (1)
Phase 3Alzheimer's DiseaseRecruiting
Est. primary completion 2029-09 · NCT07602582 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2030 (2)
April 2030 (1)
Phase 3Alzheimer's DiseaseRecruiting
Est. primary completion 2030-04 · NCT07571161 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

June 2030 (1)
Phase 2/3Alzheimer's DiseaseNot yet recruiting
Est. primary completion 2030-06-01 · NCT06996730 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

All registered studies

Research

Unlock the complete ClinicalTrials.gov registry

Research includes every linked study, indication filters, phase grouping and featured-trial cross-links.

Competitive landscape

Research

Unlock the competitor landscape

Research compares assets by shared mechanism and indication, including each competitor's stage in the relevant market.