Asset profile

faricimab

Multispecific antibody

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Approvedregulatory verdict

Evidence outlook

Approved: Age-Related Macular Degeneration

Regulatory approval supersedes design-level evidence grading; the trials behind approval are preserved below as the drug's evidence history.

track record: Partial signal

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Competitive landscape

31 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 31 same-indication.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Faricimab: this drugApprovedMultispecific antibodyAngiopoietin-2 / VEGF-A
Aflibercept (Eylea)ApprovedProtein / enzyme therapeuticVEGF-A, VEGF-A / VEGF-B / Placental Growth Factor (PlGF)
Avacincaptad Pegol (Izervay)ApprovedRna AptamerComplement C5
Brolucizumab-DbllApprovedMonoclonal antibodyVEGF-A
ChloroprocaineApprovedSmall moleculeVoltage-gated sodium channels (Nav) on sensory nerve membranes
Pegaptanib (Macugen)ApprovedSmall moleculeVEGF-A
Pegcetacoplan Ophthalmic (Syfovre)ApprovedPeptideComplement C3, Complement C3 / C3b
Ranibizumab (Lucentis)ApprovedMonoclonal antibodyVEGF-A
VerteporfinApprovedSmall moleculeBenzoporphyrin-derivative photosensitizer for photodynamic therapy
VisudyneApprovedSmall moleculePhotosensitizing agent (photodynamic therapy)
ABBV-RGX-314Phase 3Gene therapy / editingVEGF-A
ABP 938Phase 3Protein / enzyme therapeuticVEGF-A / VEGF-B / PlGF
ANX007Phase 3Monoclonal antibodyComplement C1q
CemdisiranPhase 3RNA / oligonucleotideComplement C5
CKD-701Phase 3Monoclonal antibodyVEGF-A
HLX04-OPhase 3Monoclonal antibodyVEGF-A

…and 16 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(17 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (3)
October 2026 (1)
Phase 4Age-Related Macular DegenerationActive not recruiting
Est. primary completion 2026-10-20 · NCT06795048 · CT.gov ↗
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December 2026 (2)
Phase 4Diabetic Retinopathy, Vitreous Hemorrhage Due to Diabetes MellitusEnrolling by invitation
Est. primary completion 2026-12 · NCT06191094 · CT.gov ↗
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Phase 4Diabetic Macular EdemaActive not recruiting
Est. primary completion 2026-12 · NCT05610319 · CT.gov ↗
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2027 (3)
January 2027 (1)
Phase 4Diabetic Macular EdemaActive not recruiting
Est. primary completion 2027-01-26 · NCT05224102 · CT.gov ↗
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June 2027 (1)
Early phase / not applicableDiabetic Retinopathy (DR), Diabetic Macular Edema (DME)Recruiting
Est. primary completion 2027-06-01 · NCT07520045 · CT.gov ↗
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July 2027 (1)
Phase 3Age-Related Macular DegenerationActive not recruiting
Est. primary completion 2027-07-30 · NCT05904028 · CT.gov ↗
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2028 (6)
April 2028 (1)
Phase 4Age-Related Macular DegenerationRecruiting
Est. primary completion 2028-04-30 · NCT07367282 · CT.gov ↗
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May 2028 (1)
Phase 4Presumed Ocular HistoplasmosisRecruiting
Est. primary completion 2028-05 · NCT07695298 · CT.gov ↗
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August 2028 (1)
Phase 4Polypoidal Choroidal VasculopathyRecruiting
Est. primary completion 2028-08 · NCT06709339 · CT.gov ↗
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October 2028 (1)
Phase 4Age-Related Macular DegenerationRecruiting
Est. primary completion 2028-10 · NCT07403825 · CT.gov ↗
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November 2028 (2)
Phase 1Diabetic Macular EdemaRecruiting
Est. primary completion 2028-11-17 · NCT07425522 · CT.gov ↗
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Phase 3Age-Related Macular DegenerationRecruiting
Est. primary completion 2028-11-30 · NCT07461441 · CT.gov ↗
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2029 (4)
June 2029 (1)
Early phase / not applicableAge-Related Macular DegenerationRecruiting
Est. primary completion 2029-06 · NCT07249216 · CT.gov ↗
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August 2029 (1)
Phase 2Central Serous Chorioretinopathy (CSC)Not yet recruiting
Est. primary completion 2029-08 · NCT07681167 · CT.gov ↗
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November 2029 (1)
Phase 4Diabetic Macular EdemaNot yet recruiting
Est. primary completion 2029-11-01 · NCT07753616 · CT.gov ↗
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December 2029 (1)
Phase 3Radiation Retinopathy, Visual ImpairmentRecruiting
Est. primary completion 2029-12-26 · NCT05844982 · CT.gov ↗
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2031 (1)
August 2031 (1)
Phase 3Proliferative Diabetic Retinopathy (PDR)Recruiting
Est. primary completion 2031-08 · NCT06790784 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (14)
Phase 2/3 (1)
Phase 2 (6)
Phase 1/2 (1)
Phase 1 (2)
Phase 4 (12)
Early phase / not applicable (4)
Used as active comparator (2)
Appears in other studies (3)