Asset profile

Pozelimab

Monoclonal antibody

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Phase 3underway

Evidence outlook · registrational

Registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2026-10-12.

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Competitive landscape

5 competitors in this universe: 0 direct rivals (same mechanism and indication), 5 same-class, 0 same-indication; 1 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Pozelimab: this drugPhase 3Monoclonal antibodyComplement C5
Avacincaptad Pegol (Izervay)ApprovedRna AptamerComplement C5
CemdisiranPhase 3RNA / oligonucleotideComplement C5
Eculizumab (Soliris)Phase 3Monoclonal antibodyComplement C5
Ravulizumab (Ultomiris)Phase 3Monoclonal antibodyComplement C5
ABBV-6628Phase 1/2Antibody fragmentComplement C5
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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(7 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
October 2026 (1)
Phase 3Paroxysmal Nocturnal HemoglobinuriaActive not recruiting
Est. primary completion 2026-10-12 · NCT05133531 · CT.gov ↗
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2027 (1)
May 2027 (1)
Phase 1Sporadic Inclusion Body Myositis (sIBM), Idiopathic Inflammatory MyopathiesRecruiting
Est. primary completion 2027-05-30 · NCT06479863 · CT.gov ↗
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2028 (3)
July 2028 (2)
Phase 1Geographic Atrophy (GA)Recruiting
Est. primary completion 2028-07-03 · NCT07230834 · CT.gov ↗
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Phase 3Age-related Macular Degeneration (AMD), Geographic Atrophy (GA)Recruiting
Est. primary completion 2028-07-31 · NCT06541704 · CT.gov ↗
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October 2028 (1)
Phase 3Paroxysmal Nocturnal HemoglobinuriaRecruiting
Est. primary completion 2028-10-10 · NCT05744921 · CT.gov ↗
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2030 (2)
January 2030 (1)
Phase 3Paroxysmal Nocturnal HemoglobinuriaRecruiting
Est. primary completion 2030-01-18 · NCT07154745 · CT.gov ↗
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February 2030 (1)
Phase 4CHAPLE DiseaseRecruiting
Est. primary completion 2030-02-12 · NCT07142343 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.