Asset profile

Ranibizumab · Lucentis

Monoclonal antibody

Approvedregulatory verdict

Evidence outlook

Approved — Age-Related Macular Degeneration

Regulatory approval supersedes design-level evidence grading — the trials behind approval are preserved below as the drug's evidence history.

track record: Partial signal

How the evidence outlook works ↗

Upcoming events

(8 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (2)
August 2026 (1)
Phase 1/2Age-Related Macular DegenerationActive not recruiting
Est. primary completion 2026-08-25 · NCT04567303 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

December 2026 (1)
Phase 2Diabetic Macular Edema, Diabetic RetinopathyRecruiting
Est. primary completion 2026-12 · NCT03161652 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2027 (2)
February 2027 (1)
Phase 3Age-Related Macular DegenerationActive not recruiting
Est. primary completion 2027-02-04 · NCT04657289 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

July 2027 (1)
Phase 3Age-Related Macular DegenerationRecruiting
Est. primary completion 2027-07-27 · NCT05562947 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2028 (1)
November 2028 (1)
Phase 3Age-Related Macular DegenerationRecruiting
Est. primary completion 2028-11-15 · NCT06847542 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2029 (1)
December 2029 (1)
Phase 3Age-Related Macular DegenerationRecruiting
Est. primary completion 2029-12-31 · NCT03683251 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2031 (1)
July 2031 (1)
Phase 2Age-Related Macular DegenerationEnrolling by invitation
Est. primary completion 2031-07 · NCT05210803 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2033 (1)
March 2033 (1)
Phase 3Age-Related Macular DegenerationRecruiting
Est. primary completion 2033-03 · NCT07007065 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

All registered studies

Research

Unlock the complete ClinicalTrials.gov registry

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Competitive landscape

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