Asset profile

RC28-E

Protein / enzyme therapeutic

Phase 3underway

Evidence outlook · registrational

Age-Related Macular Degeneration: registrational readout pending

Entered Phase 3 on weak signal mid-stage evidence. No upcoming registrational readout date is posted to the registry — check News for topline announcements.

NCT04270669: The study was open-label and non-randomized, included 37 participants across three dose groups, and had no placebo or active comparator. Its primary clinical endpoint was change in ETDRS best-corrected visual acuity at weeks 12 and 48, but the results and whether the endpoint was met are unavailable.

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