Asset profile

CCTx-001

Cell therapy

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Earlyevidence

Evidence outlook

Early-stage evidence only

Phase 1 / first-in-human studies establish safety, tolerability, and dosing; they are not designed to demonstrate efficacy, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

62 competitors in this universe: 0 direct rivals (same mechanism and indication), 2 same-class, 60 same-indication; 40 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
CCTx-001: this drugPhase 1/2Cell therapyIL-1RAP
BFB759Phase 2/3Monoclonal antibodyIL-1RAP
CAN04Phase 1/2Monoclonal antibodyIL-1RAP
ASTX727ApprovedSmall moleculeDecitabine/cedazuridine fixed combination (DNMT + CDA inhibition)
EnasidenibApprovedSmall moleculeIDH2
Gemtuzumab OzogamicinApprovedAntibody–drug conjugateCD33
GilteritinibApprovedSmall moleculeFLT3
MidostaurinApprovedSmall moleculeFLT3;KIT;PKC;PDGFR
OlutasidenibApprovedSmall moleculeMutant IDH1
QuizartinibApprovedSmall moleculeFLT3
RevumenibApprovedSmall moleculeMenin
Tretinoin (Vesanoid)ApprovedSmall moleculeRARA (retinoic acid receptor alpha); degrades the PML-RARA fusion oncoprotein in APL
VenetoclaxApprovedSmall moleculeBCL-2
VyxeosApprovedSmall moleculeDNA synthesis (cytarabine, antimetabolite) / Topoisomerase II
131I-ApamistamabPhase 3Monoclonal antibodyCD45
AK117Phase 3Monoclonal antibodyCD47

…and 47 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
July 2027 (1)
Phase 1/2Acute Myeloid LeukemiaNot yet recruiting
Est. primary completion 2027-07 · NCT06281847 · CT.gov ↗
What to watch
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.