Asset profile

131I-apamistamab

Monoclonal antibody

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 3 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 11 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
131I-Apamistamab: this drugPhase 3Monoclonal antibodyCD45
ASTX727ApprovedSmall moleculeDecitabine/cedazuridine fixed combination (DNMT + CDA inhibition)
EnasidenibApprovedSmall moleculeIDH2
Gemtuzumab OzogamicinApprovedAntibody–drug conjugateCD33
GilteritinibApprovedSmall moleculeFLT3
MidostaurinApprovedSmall moleculeFLT3;KIT;PKC;PDGFR
OlutasidenibApprovedSmall moleculeMutant IDH1
QuizartinibApprovedSmall moleculeFLT3
RevumenibApprovedSmall moleculeMenin
Tretinoin (Vesanoid)ApprovedSmall moleculeRARA (retinoic acid receptor alpha); degrades the PML-RARA fusion oncoprotein in APL
VenetoclaxApprovedSmall moleculeBCL-2
VyxeosApprovedSmall moleculeDNA synthesis (cytarabine, antimetabolite) / Topoisomerase II
AK117Phase 3Monoclonal antibodyCD47
APG-2575(Lisaftoclax )Phase 3Small moleculeBCL-2
AzacitidinePhase 3Small moleculeDNMT1 (DNA methyltransferase 1)
BGB-11417Phase 3—BCL-2

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(4 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
January 2027 (1)
Phase 1B-ALL, DLBCL, B ALL, Dlbcl-Ci, DLBCL Unclassifiable, DLBCL, Nos Genetic Subtypes, DLBCL Activated B-Cell Type …Recruiting
Est. primary completion 2027-01 · NCT04512716 · CT.gov ↗
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2029 (2)
February 2029 (1)
Phase 2/3Acute Myeloid LeukemiaNot yet recruiting
Est. primary completion 2029-02 · NCT07157514 · CT.gov ↗
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May 2029 (1)
Phase 1/2Non Hodgkin Lymphoma, Diffuse Large B Cell LymphomaRecruiting
Est. primary completion 2029-05 · NCT06768905 · CT.gov ↗
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2030 (1)
March 2030 (1)
Phase 1Sickling Disorder Due to Hemoglobin SRecruiting
Est. primary completion 2030-03-12 · NCT07015684 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (1)
Phase 2/3 (1)
Phase 1/2 (1)
Phase 1 (3)