Asset profile

CD123 targeted CAR-NK cells

Unknown / undisclosed

Weaksignal

Evidence outlook · lead readout

NCT06006403 · Acute Myeloid Leukemia, Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN), Relapse Leukemia, Refractory Leukemia

The reported results come from study designs that frequently fail to replicate under controlled conditions — see the rationale below.

NCT06006403: This was a non-randomized, open-label study with no comparator and only five participants. Its primary outcomes included safety and objective response rate, but results are not posted, so whether the primary outcomes were met cannot be determined.

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