Asset profile

Tagraxofusp

Unknown / undisclosed

Weaksignal

Evidence outlook · lead readout

NCT02113982 · Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN), Acute Myeloid Leukemia (AML)

The reported results come from study designs that frequently fail to replicate under controlled conditions — see the rationale below.

NCT02113982: The study was non-randomized, open-label, single-arm, and had no comparator; although complete response is a clinical disease outcome, the main efficacy cohort included only 13 patients. Its reported response rate therefore provides limited controlled evidence for tagraxofusp, and no formal between-treatment primary endpoint comparison was applicable.

How the evidence outlook works ↗

Upcoming events

(4 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
October 2027 (1)
Phase 1/2Acute Myeloid LeukemiaRecruiting
Est. primary completion 2027-10 · NCT06561152 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2028 (2)
February 2028 (1)
Phase 2Acute Myeloid LeukemiaActive not recruiting
Est. primary completion 2028-02-09 · NCT06456463 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

December 2028 (1)
Phase 1/2Acute Myeloid LeukemiaRecruiting
Est. primary completion 2028-12-31 · NCT07148180 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

2030 (1)
July 2030 (1)
Phase 2Acute Myeloid LeukemiaRecruiting
Est. primary completion 2030-07-21 · NCT05442216 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

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