Asset profile

THDBH120

Peptide

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

72 competitors in this universe: 11 direct rivals (same mechanism and indication), 1 same-class, 60 same-indication; 53 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
THDBH120: this drugPhase 2PeptideGLP-1/GIP receptor (dual)
Tirzepatide (Zepbound / Mounjaro)ApprovedPeptideGLP-1/GIP receptor (dual)
BGM0504Phase 3PeptideGLP-1/GIP receptor (dual)
BrenipatidePhase 3PeptideGLP-1/GIP receptor (dual)
EnicepatidePhase 3PeptideGLP-1 receptor, GLP-1/GIP receptor (dual)
HDM1005Phase 3PeptideGLP-1/GIP receptor (dual)
HS-20094Phase 3PeptideGLP-1/GIP receptor (dual)
RAY1225Phase 3PeptideGLP-1/GIP receptor (dual)
RibupatidePhase 3PeptideGLP-1/GIP receptor (dual)
VK2735Phase 3PeptideGLP-1/GIP receptor (dual)
NNC0519-0130Phase 2PeptideGLP-1/GIP receptor (dual)
OlatorepatidePhase 2PeptideGLP-1/GIP receptor (dual)
KP405Phase 1PeptideGLP-1/GIP receptor (dual)
Liraglutide (Saxenda / Victoza)ApprovedPeptideGLP-1 receptor
Naltrexone / Bupropion (Contrave)ApprovedSmall moleculeOpioid receptor / dopamine (combination)
Orforglipron (Foundayo)ApprovedSmall moleculeGLP-1 receptor

…and 57 more. Research shows the complete landscape.

Research

Unlock the full comparison

Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Compare head-to-head

5 further head-to-head pairs are tracked; the rosters on each shared mechanism and indication page list every rival in the race.

Upcoming events

No upcoming readouts on record for this asset.

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (1)
Phase 1 (3)