Asset profile

rexlemestrocel-L

Cell therapy

Phase 3Mechanism not established
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Phase 3underway

Evidence outlook · registrational

Heart Failure: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. No registrational readout date is posted for this indication; a Phase 3 is registered in Degenerative Disc Disease (NCT06325566); see the registry list.

Also in development:Chronic Low Back Pain · Phase 3

How the evidence outlook works ↗

Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 17 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Rexlemestrocel-L: this drugPhase 3Cell therapy—
Baxdrostat (Baxfendy)ApprovedSmall moleculeAldosterone synthase (CYP11B2)
Dapagliflozin (Farxiga / Forxiga)ApprovedSmall moleculeSGLT2
Empagliflozin (Jardiance)ApprovedSmall moleculeSGLT2
Ferric Carboxymaltose (Injectafer / Ferinject)ApprovedIron Complex (iv)Iron repletion
Ferric Derisomaltose (Monoferric / Monofer)ApprovedIron Complex (iv)Iron repletion
Finerenone (Kerendia)ApprovedSmall moleculeMineralocorticoid receptor
Furosemide (subcutaneous, scPharmaceuticals) (FUROSCIX)ApprovedSmall moleculeNKCC2
Furosemide (subcutaneous, SQ Innovation) (Lasix ONYU)ApprovedSmall moleculeNKCC2
Icodextrin (peritoneal Ultrafiltration) (Extraneal)ApprovedDevice Solution (peritoneal Dialysis)Peritoneal ultrafiltration
Isosorbide Dinitrate / Hydralazine (BiDil)ApprovedSmall moleculeHydralazine/isosorbide dinitrate (fixed combination)
Ivabradine (Corlanor)ApprovedSmall moleculeIf (funny) channel
Mavacamten (Camzyos)ApprovedSmall moleculeCardiac myosin (inhibitor)
Sacubitril / Valsartan (Entresto)ApprovedSmall moleculeNeprilysin + Angiotensin II receptor (dual)
Sotagliflozin (Inpefa)ApprovedSmall moleculeSGLT1/2 (dual)
Tolvaptan (Samsca / Jinarc)ApprovedSmall moleculeVasopressin V2 receptor

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (1)
July 2027 (1)
Phase 3Degenerative Disc DiseaseActive not recruiting
Est. primary completion 2027-07 · NCT06325566 · CT.gov ↗
What to watch
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (3)
Phase 1/2 (1)