Asset profile
AC01
Small molecule
Evidence outlook · lead readout
NCT05642507 · Heart Failure With Reduced Ejection Fraction
The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.
NCT05642507: The study used randomization, matching placebo, and quadruple blinding, but enrolled only 58 participants across multiple dose cohorts and was primarily designed to assess short-term safety and tolerability rather than a hard clinical outcome. No primary-endpoint results or statistical comparison have been posted, so whether the primary endpoint was met is unknown.
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Upcoming events
(1 total)
Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.
2028 (1)
May 2028 (1)
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