Asset profile

HSK47388

Small molecule

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Earlyevidence

Evidence outlook

Mid-stage studies underway, no completed readout

Phase 2 studies are registered but none has completed a readout, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

Also in development:Ulcerative Colitis · Phase 2

How the evidence outlook works ↗

Competitive landscape

116 competitors in this universe: 2 direct rivals (same mechanism and indication), 0 same-class, 114 same-indication; 103 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
HSK47388: this drugPhase 2Small moleculeIL-23 receptor
IcotrokinraApprovedPeptideIL-23 receptor
HS-20118Phase 2PeptideIL-23 receptor
Adalimumab (Humira)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Aacf (Idacio)Approved—TNF-alpha
Adalimumab-Aaty (Yuflyma)Approved—TNF-alpha
Adalimumab-Adaz (Hyrimoz)Approved—TNF-alpha
Adalimumab-Adbm (Cyltezo)ApprovedMonoclonal antibodyTNF-alpha
Adalimumab-Afzb (Abrilada)Approved—TNF-alpha
Adalimumab-Aqvh (Yusimry)Approved—TNF-alpha
Adalimumab-Atto (Amjevita)Approved—TNF-alpha
Adalimumab-Bwwd (Hadlima)Approved—TNF-alpha
Adalimumab-Fkjp (Hulio)Approved—TNF-alpha
Adalimumab-Ryvk (Simlandi)Approved—TNF-alpha
Apremilast (Otezla)ApprovedSmall moleculePDE4
Balsalazide Disodium (Colazal)Approved—Aminosalicylate

…and 101 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

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Upcoming events

(2 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Phase 2PsoriasisNot yet recruiting
Est. primary completion 2026-12-20 · NCT07158268 · CT.gov ↗
What to watch
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2027 (1)
October 2027 (1)
Phase 2Ulcerative ColitisRecruiting
Est. primary completion 2027-10-15 · NCT07335055 · CT.gov ↗
What to watch
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 2 (2)
Phase 1 (2)