Asset profile

DR10624

Protein / enzyme therapeutic

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Earlyevidence

Evidence outlook

Early-stage evidence only

Phase 1 / first-in-human studies establish safety, tolerability, and dosing; they are not designed to demonstrate efficacy, so no evidence signal is assigned yet. The first graded signal arrives with a completed confirmatory readout.

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Competitive landscape

60 competitors in this universe: 0 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 8 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
DR10624: this drugPhase 3Protein / enzyme therapeuticGLP-1R; GCGR; FGF21R
Liraglutide (Saxenda / Victoza)ApprovedPeptideGLP-1 receptor
Naltrexone / Bupropion (Contrave)ApprovedSmall moleculeOpioid receptor / dopamine (combination)
Orforglipron (Foundayo)ApprovedSmall moleculeGLP-1 receptor
Orlistat (Xenical / Alli)ApprovedSmall moleculePancreatic/gastric lipase
Phentermine / Topiramate (Qsymia)ApprovedSmall moleculeNoradrenergic/anticonvulsant (combination)
Semaglutide (Wegovy / Ozempic / Rybelsus)ApprovedPeptideGLP-1 receptor
Setmelanotide (Imcivree)ApprovedPeptideMC4R
Tirzepatide (Zepbound / Mounjaro)ApprovedPeptideGLP-1/GIP receptor (dual)
AleniglipronPhase 3Small moleculeGLP-1 receptor
AmycretinPhase 3PeptideGLP-1 receptor, Amylin receptor
ApitegromabPhase 3Monoclonal antibodyActivin/myostatin type II receptor
ARD-101Phase 3Small moleculeBitter taste receptor (gut)
ASC30Phase 3Small moleculeGLP-1 receptor
AZD6234Phase 3PeptideAmylin receptor
BGM0504Phase 3PeptideGLP-1/GIP receptor (dual)

…and 45 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(4 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
December 2026 (1)
Early phase / not applicableHypertriglyceridemia, Carotid Atherosclerotic PlaquesEnrolling by invitation
Est. primary completion 2026-12-31 · NCT07050134 · CT.gov ↗
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2028 (1)
April 2028 (1)
Phase 2HypertriglyceridemiaNot yet recruiting
Est. primary completion 2028-04 · NCT07848880 · CT.gov ↗
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2029 (1)
February 2029 (1)
Phase 3Severe Hypertriglyceridemia (sHTG), HypertriglyceridemiaNot yet recruiting
Est. primary completion 2029-02-14 · NCT07693777 · CT.gov ↗
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2030 (1)
June 2030 (1)
Phase 3Severe HypertriglyceridemiaNot yet recruiting
Est. primary completion 2030-06 · NCT07680829 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (2)
Phase 2 (3)
Phase 1 (1)
Early phase / not applicable (1)