Asset profile

CPO301

Antibody–drug conjugate

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Phase 3underway

Evidence outlook · registrational

Non-Small Cell Lung Cancer: registrational readout pending

Its supporting mid-stage evidence has not yet been graded on this platform. Registrational readout expected around 2026-12-12.

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Competitive landscape

102 competitors in this universe: 41 direct rivals (same mechanism and indication), 1 same-class, 60 same-indication; 58 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
CPO301: this drugPhase 3Antibody–drug conjugateEGFR
GefitinibApprovedSmall moleculeEGFR
LazertinibApprovedSmall moleculeEGFR
Osimertinib (Tagrisso)ApprovedSmall moleculeEGFR
SunvozertinibApprovedSmall moleculeEGFR
AlflutinibPhase 3Small moleculeEGFR
AlmonertinibPhase 3Small moleculeEGFR
BefotertinibPhase 3Small moleculeEGFR
BPI-7711Phase 3Small moleculeEGFR
FHND9041Phase 3Small moleculeEGFR
IcotinibPhase 3Small moleculeEGFR
JMT101Phase 3Monoclonal antibodyEGFR
LimertinibPhase 3Small moleculeEGFR, EGFR T790M (resistant mutant, selective over wild-type EGFR)
PLB1004Phase 3Small moleculeEGFR
SH-1028Phase 3Small moleculeEGFR
TY-9591Phase 3Small moleculeEGFR

…and 87 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(14 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (2)
November 2026 (1)
Phase 2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2026-11-30 · NCT07256509 · CT.gov ↗
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December 2026 (1)
Phase 3Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2026-12-12 · NCT07376382 · CT.gov ↗
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2027 (6)
May 2027 (1)
Phase 1Cancer, Cancer, LungRecruiting
Est. primary completion 2027-05 · NCT05948865 · CT.gov ↗
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June 2027 (1)
Phase 1/2Advanced Solid Tumors, Breast CancerNot yet recruiting
Est. primary completion 2027-06-15 · NCT06775236 · CT.gov ↗
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September 2027 (1)
Phase 3Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2027-09-30 · NCT07633873 · CT.gov ↗
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October 2027 (1)
Phase 1/2Advanced Solid TumorsRecruiting
Est. primary completion 2027-10-30 · NCT07241936 · CT.gov ↗
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December 2027 (2)
Phase 3Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2027-12-30 · NCT07442565 · CT.gov ↗
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Phase 1Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2027-12-31 · NCT07692048 · CT.gov ↗
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2028 (2)
September 2028 (1)
Phase 3Head and Neck Squamous Cell CarcinomaNot yet recruiting
Est. primary completion 2028-09-15 · NCT07758621 · CT.gov ↗
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December 2028 (1)
Phase 3Locally Advanced/Metastatic/Recurrent ESCCNot yet recruiting
Est. primary completion 2028-12-31 · NCT07417735 · CT.gov ↗
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2029 (4)
February 2029 (1)
Phase 1/2Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2029-02-28 · NCT07472647 · CT.gov ↗
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April 2029 (1)
Phase 3Recurrent or Metastatic Breast CancerNot yet recruiting
Est. primary completion 2029-04-01 · NCT07406542 · CT.gov ↗
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September 2029 (1)
Phase 3Non-Small Cell Lung CancerNot yet recruiting
Est. primary completion 2029-09-30 · NCT07672223 · CT.gov ↗
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December 2029 (1)
Phase 2/3Esophageal Squamous Cell CarcinomaNot yet recruiting
Est. primary completion 2029-12-30 · NCT07251062 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (8)
Phase 2/3 (1)
Phase 2 (2)
Phase 1/2 (3)
Phase 1 (2)
Early phase / not applicable (1)