Asset profile

Camizestrant

Small molecule

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Approvedregulatory verdict

Evidence outlook

Approved: hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative,... (FDA)

This approval is for an indication outside this terminal's covered markets; the covered program shown here is investigational. Regulatory approval supersedes design-level evidence grading for the approved use.

track record: Weak signal

Source for the program status

How the evidence outlook works ↗

Competitive landscape

67 competitors in this universe: 7 direct rivals (same mechanism and indication), 0 same-class, 60 same-indication; 29 further along in development.

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DrugStageModalityMechanismEvidence signalReported efficacygraded featured trials
Camizestrant: this drugPhase 3Small moleculeEstrogen receptor
ElacestrantApprovedSmall moleculeEstrogen receptor
Fulvestrant (Faslodex)ApprovedSmall moleculeEstrogen receptor
ImlunestrantApprovedSmall moleculeEstrogen receptor
TamoxifenApprovedSmall moleculeEstrogen receptor
VepdegestrantApprovedSmall moleculeEstrogen receptor
GiredestrantPhase 3Small moleculeEstrogen receptor
PalazestrantPhase 3Small moleculeEstrogen receptor
Abemaciclib (Verzenio)ApprovedSmall moleculeCDK4 and CDK6
Alpelisib (BYL719)ApprovedSmall moleculePI3K-alpha
AnastrozoleApprovedSmall moleculeAromatase
CapecitabineApprovedSmall moleculeFluoropyrimidine (antimetabolite)
CapivasertibApprovedSmall moleculeAKT (inhibitor)
Datopotamab DeruxtecanApprovedAntibody–drug conjugateTROP2
DenosumabApprovedMonoclonal antibodyRANKL
DocetaxelApprovedSmall moleculeMicrotubules (tubulin)

…and 52 more. Research shows the complete landscape.

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Research adds each competitor's evidence grade and sourced trial results, aligned per race, so you can see who actually has the data.

Upcoming events

(8 total)

Estimated primary-completion dates from ClinicalTrials.gov. These are registry estimates, never confirmed readout dates; they can move as trials progress.

2027 (4)
April 2027 (1)
Phase 3HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2027-04-20 · NCT05774951 · CT.gov ↗
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May 2027 (1)
Phase 1/2HR+/HER2- Metastatic Breast CancerActive not recruiting
Est. primary completion 2027-05-28 · NCT04644068 · CT.gov ↗
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August 2027 (1)
Phase 1/2HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2027-08-04 · NCT06188520 · CT.gov ↗
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December 2027 (1)
Phase 2HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2027-12-28 · NCT07427394 · CT.gov ↗
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2028 (1)
February 2028 (1)
Phase 2HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2028-02 · NCT07195227 · CT.gov ↗
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2029 (2)
February 2029 (1)
Phase 3HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2029-02-28 · NCT07647328 · CT.gov ↗
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December 2029 (1)
Phase 3HR+/HER2- Metastatic Breast CancerRecruiting
Est. primary completion 2029-12-18 · NCT06380751 · CT.gov ↗
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2030 (1)
March 2030 (1)
Phase 3HR+/HER2- Metastatic Breast CancerActive not recruiting
Est. primary completion 2030-03-04 · NCT05952557 · CT.gov ↗
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See the full readout calendar ↗

All registered studies

Every ClinicalTrials.gov study of this drug's own program, grouped by indication and phase. Research unlocks the studies themselves: titles, statuses, dates and featured-trial cross-links.

Phase 3 (6)
Phase 2 (4)
Phase 1/2 (2)
Phase 1 (9)
Appears in other studies (1)