Asset profile

(Z)-endoxifen

Small molecule

Partialsignal

Evidence outlook · lead readout

NCT03931928 · Breast Cancer, DCIS

The completed lead evidence is positive, with design limits that temper confidence — see the rationale below for exactly which.

NCT03931928: This was a randomized, participant-masked, placebo-controlled study of 356 patients, but its primary endpoint was a pharmacokinetic concentration threshold rather than a clinical or endoscopic outcome. Because no results or statistical comparison are posted, it cannot establish whether the primary endpoint was met.

How the evidence outlook works ↗

Upcoming events

(1 total)

Estimated primary-completion dates from ClinicalTrials.gov — registry estimates, never confirmed readout dates; they can move as trials progress.

2026 (1)
November 2026 (1)
Phase 2HR+/HER2- Metastatic Breast CancerActive not recruiting
Est. primary completion 2026-11 · NCT05607004 · CT.gov ↗
What to watch

Research analysis

Source-grounded endpoint goals, benchmarks, comparator context, and caveats for this readout are included with Research.

See the full readout calendar ↗

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